Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
RZ Goldstein, ND Volkow - Nature reviews neuroscience, 2011 - nature.com
The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …
from disruption of subcortical reward circuits. However, imaging studies in addictive …
The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex
A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …
addiction has extended the scope of inquiry from the putative reward-related subcortical …
Factors modulating neural reactivity to drug cues in addiction: a survey of human neuroimaging studies
Human neuroimaging studies suggest that neural cue reactivity is strongly associated with
indices of drug use, including addiction severity and treatment success. However, little is …
indices of drug use, including addiction severity and treatment success. However, little is …
Neural substrates of smoking cue reactivity: a meta-analysis of fMRI studies
Reactivity to smoking-related cues may be an important factor that precipitates relapse in
smokers who are trying to quit. The neurobiology of smoking cue reactivity has been …
smokers who are trying to quit. The neurobiology of smoking cue reactivity has been …
Interoception and drug addiction
The role of interoception and its neural basis with relevance to drug addiction is reviewed.
Interoception consists of the receiving, processing, and integrating body-relevant signals …
Interoception consists of the receiving, processing, and integrating body-relevant signals …
Mindfulness training targets neurocognitive mechanisms of addiction at the attention-appraisal-emotion interface
Prominent neuroscience models suggest that addictive behavior occurs when
environmental stressors and drug-relevant cues activate a cycle of cognitive, affective, and …
environmental stressors and drug-relevant cues activate a cycle of cognitive, affective, and …
Brain correlates of craving for online gaming under cue exposure in subjects with Internet gaming addiction and in remitted subjects
This study aimed to evaluate brain correlates of cue‐induced craving to play online games
in subjects with Internet gaming addiction (IGA), subjects in remission from IGA and controls …
in subjects with Internet gaming addiction (IGA), subjects in remission from IGA and controls …
Reward processing in obesity, substance addiction and non‐substance addiction
Similarities and differences between obesity and addiction are a prominent topic of ongoing
research. We conducted an activation likelihood estimation meta‐analysis on 87 studies in …
research. We conducted an activation likelihood estimation meta‐analysis on 87 studies in …
The clinical relevance of attentional bias in substance use disorders
Individuals with substance use disorders typically show an “attentional bias” for substance-
related cues: Those cues are able to grab and hold the attention, in preference to other cues …
related cues: Those cues are able to grab and hold the attention, in preference to other cues …
Neural mechanisms of incentive salience in naturalistic human vision
What role does reward play in real-world human vision? Reward coding in the midbrain is
thought to cause the rapid prioritization of reward-associated visual stimuli. However …
thought to cause the rapid prioritization of reward-associated visual stimuli. However …