Recent progress in mass spectrometry-based urinary proteomics

N Joshi, K Garapati, V Ghose, RK Kandasamy… - Clinical Proteomics, 2024 - Springer
Serum or plasma is frequently utilized in biomedical research; however, its application is
impeded by the requirement for invasive sample collection. The non-invasive nature of urine …

Biomarker discovery in mass spectrometry‐based urinary proteomics

S Thomas, L Hao, WA Ricke, L Li - PROTEOMICS–Clinical …, 2016 - Wiley Online Library
Urinary proteomics has become one of the most attractive topics in disease biomarker
discovery. MS‐based proteomic analysis has advanced continuously and emerged as a …

Advancing urinary protein biomarker discovery by data-independent acquisition on a quadrupole-orbitrap mass spectrometer

J Muntel, Y Xuan, ST Berger, L Reiter… - Journal of proteome …, 2015 - ACS Publications
The promises of data-independent acquisition (DIA) strategies are a comprehensive and
reproducible digital qualitative and quantitative record of the proteins present in a sample …

Biomarkers that differentiate benign prostatic hyperplasia from prostate cancer: A literature review

CJ McNally, MW Ruddock, T Moore… - Cancer management …, 2020 - Taylor & Francis
Prediction of prostate cancer in primary care is typically based upon serum total prostate-
specific antigen (tPSA) and digital rectal examination results. However, these tests lack …

Prostate cancer proteomics: clinically useful protein biomarkers and future perspectives

P Intasqui, RP Bertolla, MV Sadi - Expert review of proteomics, 2018 - Taylor & Francis
Introduction: Although prostate cancer constitutes one of the most important, death-related
diseases in the male population, there is still a need for identification of sensitive biomarkers …

Urinary biomarkers in prostate cancer detection and monitoring progression

D Wu, J Ni, J Beretov, P Cozzi, M Willcox… - Critical reviews in …, 2017 - Elsevier
Prostate cancer (CaP) is the most common cancer in men and the second leading cause of
cancer deaths in males in Australia. Although serum prostate-specific antigen (PSA) has …

Novel potential serological prostate cancer biomarkers using CT100+ cancer antigen microarray platform in a multi-cultural South African cohort

HA Adeola, M Smith, L Kaestner, JM Blackburn… - …, 2016 - pmc.ncbi.nlm.nih.gov
There is a growing need for high throughput diagnostic tools for early diagnosis and
treatment monitoring of prostate cancer (PCa) in Africa. The role of cancer-testis antigens …

LC-MSE, Multiplex MS/MS, Ion Mobility, and Label-Free Quantitation in Clinical Proteomics

GHMF Souza, PC Guest… - … Techniques: Methods and …, 2017 - Springer
Proteomic tools can only be implemented in clinical settings if high-throughput, automated,
sensitive, and accurate methods are developed. This has driven researchers to the edge of …

[HTML][HTML] The prospect and challenges to the flow of liquid biopsy in Africa

DO Temilola, M Wium, TH Coulidiati, HA Adeola… - Cells, 2019 - mdpi.com
Liquid biopsy technologies have the potential to transform cancer patient management as it
offers non-invasive diagnosis and real-time monitoring of disease progression and treatment …

[HTML][HTML] Detection of cancer-associated gene mutations in urinary cell-free DNA among prostate cancer patients in South Africa

DO Temilola, M Wium, J Paccez, AS Salukazana… - Genes, 2023 - mdpi.com
Prostate cancer (PCa) is the most common cause of cancer death among African men. The
presence of tumor-specific variations in cell-free DNA (cfDNA), such as mutations …