Mitochondrial DNA is released by shock and activates neutrophils via p38 map kinase
Q Zhang, K Itagaki, CJ Hauser - Shock, 2010 - journals.lww.com
Bacterial DNA (bDNA) can activate an innate-immune stimulatory" danger “response via toll-
like receptor 9 (TLR9). Mitochondrial DNA (mtDNA) is unique among endogenous …
like receptor 9 (TLR9). Mitochondrial DNA (mtDNA) is unique among endogenous …
Neutrophil-derived circulating free DNA (cf-DNA/NETs): a potential prognostic marker for posttraumatic development of inflammatory second hit and sepsis
S Margraf, T Lögters, J Reipen, J Altrichter, M Scholz… - Shock, 2008 - journals.lww.com
The release of" neutrophil extracellular traps"(NETs) has been identified as a novel immune
response in innate immunity. Neutrophil extracellular traps are composed of neutrophil …
response in innate immunity. Neutrophil extracellular traps are composed of neutrophil …
Calcium ion channels: roles in infection and sepsis mechanisms of calcium channel blocker benefits in immunocompromised patients at risk for infection
JA D'Elia, LA Weinrauch - International journal of molecular sciences, 2018 - mdpi.com
Immunosuppression may occur for a number of reasons related to an individual's frailty,
debility, disease or from therapeutic iatrogenic intervention or misadventure. A large …
debility, disease or from therapeutic iatrogenic intervention or misadventure. A large …
Highly Pathogenic H5N1 Avian Influenza Virus Induces Extracellular Ca2+ Influx, Leading to Apoptosis in Avian Cells
M Ueda, T Daidoji, A Du, CS Yang, MS Ibrahim… - Journal of …, 2010 - Am Soc Microbiol
In this study, we show that the highly pathogenic H5N1 avian influenza virus
(AIV)(A/crow/Kyoto/53/04 and A/chicken/Egypt/CL6/07) induced apoptosis in duck …
(AIV)(A/crow/Kyoto/53/04 and A/chicken/Egypt/CL6/07) induced apoptosis in duck …
Therapeutically targeting microvascular leakage in experimental hemorrhagic SHOCK: a systematic review and meta-analysis
ALI van Leeuwen, MP Borgdorff, NAM Dekker… - Shock, 2021 - journals.lww.com
Background: Microvascular leakage is proposed as main contributor to disturbed
microcirculatory perfusion following hemorrhagic shock and fluid resuscitation, leading to …
microcirculatory perfusion following hemorrhagic shock and fluid resuscitation, leading to …
A new model of severe hemorrhagic shock in rats
T Rönn, S Lendemans, H de Groot… - Comparative …, 2011 - ingentaconnect.com
We here introduce a fixed-pressure model of hemorrhagic shock in rats that maximizes
effects on mean arterial blood pressure (MAP) during shock and yet maintains high …
effects on mean arterial blood pressure (MAP) during shock and yet maintains high …
Induced hypothermia attenuates the acute lung injury in hemorrhagic shock
K Kim, W Kim, JE Rhee, YH Jo, JH Lee… - Journal of Trauma …, 2010 - journals.lww.com
Background: In previous animal studies, induction of therapeutic hypothermia (HT) in
hemorrhagic shock (HS) had beneficial effects on the hemodynamic and metabolic …
hemorrhagic shock (HS) had beneficial effects on the hemodynamic and metabolic …
The therapeutic effect and mechanism of niacin on acute lung injury in a rat model of hemorrhagic shock: Down-regulation of the reactive oxygen species–dependent …
KY Jeong, GJ Suh, WY Kwon, KS Kim… - Journal of Trauma …, 2015 - journals.lww.com
BACKGROUND The purpose of the current study was to investigate the protective effect of
niacin on acute lung injury by the down-regulation of the nuclear factor κB (NF-κB) pathway …
niacin on acute lung injury by the down-regulation of the nuclear factor κB (NF-κB) pathway …
Influence of the timing of internal fixation of femur fractures during shock resuscitation on remote organ damage
BM Hardy, O Yoshino, AW Quail… - ANZ Journal of …, 2015 - Wiley Online Library
Background Reamed intramedullary nailing is the gold standard for management of femur
fractures. Nailing within 24 h is proven to reduce complications from ongoing bleeding, soft …
fractures. Nailing within 24 h is proven to reduce complications from ongoing bleeding, soft …
Resuscitation with Na+/H+ exchanger inhibitor in traumatic haemorrhagic shock: Cardiopulmonary performance, oxygen transport and tissue inflammation
D Wu, J Qi, H Dai, H Doods… - Clinical and …, 2010 - Wiley Online Library
The aim of the present study was to examine the effects of inhibition of the Na+/H+
exchanger (NHE‐1) on cardiopulmonary performance, oxygen carrying capacity and tissue …
exchanger (NHE‐1) on cardiopulmonary performance, oxygen carrying capacity and tissue …