Colorimetric detection of DNA using unmodified metallic nanoparticles and peptide nucleic acid probes

R Kanjanawarut, X Su - Analytical chemistry, 2009 - ACS Publications
We have developed a colorimetric assay for DNA detection based on the aggregation of
unmodified metallic nanoparticles. Charge neutral peptide nucleic acids (PNA) are used as …

Robust ligand shells for biological applications of gold nanoparticles

L Duchesne, D Gentili, M Comes-Franchini, DG Fernig - Langmuir, 2008 - ACS Publications
An important point regarding the development of stable biofunctional nanoparticles for
biomedical applications is their potential for aspecific interactions with the molecules of the …

Novel synthetic route to peptide-capped gold nanoparticles

T Serizawa, Y Hirai, M Aizawa - Langmuir, 2009 - ACS Publications
A novel synthetic route to peptide-capped gold nanoparticles was demonstrated herein.
Tetrachloroaurate ions were reduced with 2-[4-(2-hydroxyethyl)-1-piperazinyl] …

Single gold nanoparticle localized surface plasmon resonance spectral imaging for quantifying binding constant of carbohydrate–protein interaction

X Liu, Q Zhang, Y Tu, W Zhao, H Gai - Analytical Chemistry, 2013 - ACS Publications
Quantifying carbohydrate–protein (ligand–receptor) interactions is important to understand
diverse biological processes and to develop new diagnostic and therapeutic methods. We …

A “turn-off” SERS assay of heparin with high selectivity based on heparin–peptide complex and Raman labelled gold nanoparticles

G Qu, G Zhang, Z Wu, A Shen, J Wang, J Hu - Biosensors and …, 2014 - Elsevier
Stable SERS response originating from gold nanoparticles (Au NPs) is demonstrated for the
first time to be suitable for detection of heparin with high selectivity. Herein we report a novel …

Identification and sequence composition characterization of chondroitin sulfate-binding peptides through peptide array screening

KC Butterfield, M Caplan, A Panitch - Biochemistry, 2010 - ACS Publications
Chondroitin sulfate (CS) is an important glycosaminoglycan that has been implicated in
several disease processes, such as cancer and spinal cord injury. However, few studies …

Features of thiolated ligands promoting resistance to ligand exchange in self-assembled monolayers on gold nanoparticles

X Chen, WW Qoutah, P Free, J Hobley… - Australian Journal of …, 2012 - CSIRO Publishing
An important feature necessary for biological stability of gold nanoparticles is resistance to
ligand exchange. Here, we design and synthesize self-assembled monolayers of mixtures of …

Synthesis of silver nanoparticles with monovalently functionalized self-assembled monolayers

P Free, D Paramelle, M Bosman… - Australian Journal of …, 2012 - CSIRO Publishing
The importance of having nanoparticles that are soluble, stable, and that have no non-
specific binding is often overlooked, but essential for their use in biology. This is particularly …

Rational identification and characterisation of peptide ligands for targeting polysialic acid

DG Shastry, FJ Irudayanathan, A Williams, M Koffas… - Scientific reports, 2020 - nature.com
Abstract The alpha-2, 8-linked form of the polysaccharide polysialic acid (PSA) has
widespread implications in physiological and pathological processes, ranging from …

Nanoradiopharmaceuticals for nanomedicine: building the future

MA Vergara Wasserman… - Recent Patents on …, 2014 - ingentaconnect.com
The number of patents that is increasing in the field of radiopharmacy from 2000 until 2013
are over 4500 patents that have been deposited nationaly and internationally. However …