Use of 3D anatomical models in mock circulatory loops for cardiac medical device testing

M Rocchi, M Ingram, P Claus, J D'hooge… - Artificial …, 2023 - Wiley Online Library
Abstract Introduction Mock circulatory loops (MCLs) are mechanical representations of the
cardiovascular system largely used to test the hemodynamic performance of cardiovascular …

Fully-coupled FSI computational analyses in the ascending thoracic aorta using patient-specific conditions and anisotropic material properties

E Vignali, E Gasparotti, S Celi, S Avril - Frontiers in Physiology, 2021 - frontiersin.org
Computational hemodynamics has become increasingly important within the context of
precision medicine, providing major insight in cardiovascular pathologies. However, finding …

An integrated in-vitro and in-silico workflow to study the pulmonary bifurcation hemodynamics

BM Fanni, E Gasparotti, E Vignali, C Capelli… - Computers & …, 2023 - Elsevier
Abstract Tetralogy of Fallot (ToF) is the most common congenital heart disease. In this work,
hemodynamics of pulmonary arteries (PA) in ToF patients was investigated using patient …

A novel formulation for the study of the ascending aortic fluid dynamics with in vivo data

K Capellini, E Gasparotti, U Cella, E Costa… - Medical Engineering & …, 2021 - Elsevier
Numerical simulations to evaluate thoracic aortic hemodynamics include a computational
fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD …

[HTML][HTML] The hemodynamic effect of modified blalock–taussig shunt morphologies: A computational analysis based on reduced order modeling

E Kardampiki, E Vignali, D Haxhiademi, D Federici… - Electronics, 2022 - mdpi.com
The Modified Blalock Taussig Shunt (MBTS) is one of the most common palliative operations
in case of cyanotic heart diseases. Thus far, the decision on the position, size, and geometry …

Uncertainty quantification in the in vivo image-based estimation of local elastic properties of vascular walls

BM Fanni, MN Antonuccio, A Pizzuto, S Berti… - Journal of …, 2023 - mdpi.com
Introduction: Patient-specific computational models are a powerful tool for planning
cardiovascular interventions. However, the in vivo patient-specific mechanical properties of …

A hybrid mock circulatory loop integrated with a LED-PIV system for the investigation of AAA compliant phantoms

F Bardi, E Gasparotti, E Vignali… - … in Bioengineering and …, 2024 - frontiersin.org
Background Cardiovascular diseases remain a leading cause of morbidity and mortality
worldwide and require extensive investigation through in-vitro studies. Mock Circulatory …

Coupling synthetic and real-world data for a deep learning-based segmentation process of 4d flow mri

S Garzia, MA Scarpolini, M Mazzoli, K Capellini… - Computer Methods and …, 2023 - Elsevier
Background and objective Phase contrast magnetic resonance imaging (4D flow MRI) is an
imaging technique able to provide blood velocity in vivo and morphological information. This …

An image-based approach for the estimation of arterial local stiffness in vivo

S Celi, E Gasparotti, K Capellini, F Bardi… - … in Bioengineering and …, 2023 - frontiersin.org
The analysis of mechanobiology of arterial tissues remains an important topic of research for
cardiovascular pathologies evaluation. In the current state of the art, the gold standard to …

A high-fidelity personalised 3d printed simulator for the left atrial appendage occlusion procedure

BM Fanni, E Gasparotti, A Esposito, F Danielli… - Rapid Prototy** …, 2025 - emerald.com
Purpose This study aims to develop a realistic 3D printing-based simulator for the training
and planning of the left atrial appendage occlusion (LAAO) to be used in the cath lab …