[HTML][HTML] Translating state-of-the-art spinal cord MRI techniques to clinical use: A systematic review of clinical studies utilizing DTI, MT, MWF, MRS, and fMRI

AR Martin, I Aleksanderek, J Cohen-Adad… - NeuroImage: Clinical, 2016 - Elsevier
Background A recent meeting of international imaging experts sponsored by the
International Spinal Research Trust (ISRT) and the Wings for Life Foundation identified 5 …

From animal models to human disease: a genetic approach for personalized medicine in ALS

V Picher-Martel, PN Valdmanis, PV Gould… - Acta neuropathologica …, 2016 - Springer
Abstract Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in
adults. Classical ALS is characterized by the death of upper and lower motor neurons …

SCT: Spinal Cord Toolbox, an open-source software for processing spinal cord MRI data

B De Leener, S Lévy, SM Dupont, VS Fonov, N Stikov… - Neuroimage, 2017 - Elsevier
For the past 25 years, the field of neuroimaging has witnessed the development of several
software packages for processing multi-parametric magnetic resonance imaging (mpMRI) to …

Pain in amyotrophic lateral sclerosis

A Chiò, G Mora, G Lauria - The Lancet Neurology, 2017 - thelancet.com
Pain is a largely neglected symptom in patients with amyotrophic lateral sclerosis (ALS)
although it is reported by most of these patients. It occurs at all stages of the disease and can …

Identification of GGC repeat expansion in the NOTCH2NLC gene in amyotrophic lateral sclerosis

Y Yuan, Z Liu, X Hou, W Li, J Ni, L Huang, Y Hu, P Liu… - Neurology, 2020 - neurology.org
Objective To determine whether the GGC repeats in the NOTCH2NLC gene contribute to
amyotrophic lateral sclerosis (ALS). Methods In this study, 545 patients with ALS and 1,305 …

Diagnostics of amyotrophic lateral sclerosis: up to date

I Štětkářová, E Ehler - Diagnostics, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by gradual loss of upper and lower motor neurons and their pathways, usually …

Spinal cord imaging in amyotrophic lateral sclerosis: historical concepts—novel techniques

MM El Mendili, G Querin, P Bede, PF Pradat - Frontiers in neurology, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neuron disease
with no effective disease modifying therapies at present. Spinal cord degeneration is a …

Amyotrophic lateral sclerosis: Current perspectives from basic research to the clinic

R Mancuso, X Navarro - Progress in Neurobiology, 2015 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by
progressive degeneration of upper and lower motoneurons, leading to muscle weakness …

Non-motor symptoms in patients with amyotrophic lateral sclerosis: current state and future directions

B Bjelica, MB Bartels, J Hesebeck-Brinckmann… - Journal of …, 2024 - Springer
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the progressive degeneration of both upper and lower motor neurons. A defining …

“Switchboard” malfunction in motor neuron diseases: Selective pathology of thalamic nuclei in amyotrophic lateral sclerosis and primary lateral sclerosis

RH Chipika, E Finegan, SLH Shing, MC McKenna… - NeuroImage: Clinical, 2020 - Elsevier
The thalamus is a key cerebral hub relaying a multitude of corticoefferent and corticoafferent
connections and mediating distinct extrapyramidal, sensory, cognitive and behavioural …