Genetics of taste receptors

AA Bachmanov, NP Bosak, C Lin… - Current …, 2014 - ingentaconnect.com
Taste receptors function as one of the interfaces between internal and external milieus.
Taste receptors for sweet and umami (T1R [taste receptor, type 1]), bitter (T2R [taste …

Understanding phylogenetic incongruence: lessons from phyllostomid bats

LM Dávalos, AL Cirranello, JH Geisler… - Biological …, 2012 - Wiley Online Library
All characters and trait systems in an organism share a common evolutionary history that
can be estimated using phylogenetic methods. However, differential rates of change and the …

Major taste loss in carnivorous mammals

P Jiang, J Josue, X Li, D Glaser, W Li, JG Brand… - Proceedings of the …, 2012 - pnas.org
Mammalian sweet taste is primarily mediated by the type 1 taste receptor Tas1r2/Tas1r3,
whereas Tas1r1/Tas1r3 act as the principal umami taste receptor. Bitter taste is mediated by …

Diet shapes the evolution of the vertebrate bitter taste receptor gene repertoire

D Li, J Zhang - Molecular biology and evolution, 2014 - academic.oup.com
Vertebrate Tas2r taste receptors bind to bitter compounds, which are typically poisonous, to
elicit bitter sensation to prevent the ingestion of toxins. Previous studies noted a marked …

Gene losses in the common vampire bat illuminate molecular adaptations to blood feeding

M Blumer, T Brown, MB Freitas, AL Destro… - Science …, 2022 - science.org
Vampire bats are the only mammals that feed exclusively on blood. To uncover genomic
changes associated with this dietary adaptation, we generated a haplotype-resolved …

Pseudogenization of the Umami Taste Receptor Gene Tas1r1 in the Giant Panda Coincided with its Dietary Switch to Bamboo

H Zhao, JR Yang, H Xu, J Zhang - Molecular biology and …, 2010 - academic.oup.com
Although it belongs to the order Carnivora, the giant panda is a vegetarian with 99% of its
diet being bamboo. The draft genome sequence of the giant panda shows that its umami …

Eyeless cave-dwelling Leptonetela spiders still rely on light

K Wang, J Wang, B Liang, J Chang, Y Zhu, J Chen… - Science …, 2023 - science.org
Subterranean animals living in perpetual darkness may maintain photoresponse. However,
the evolutionary processes behind the conflict between eye loss and maintenance of the …

Genomic evidence for adaptation by gene duplication

W Qian, J Zhang - Genome research, 2014 - genome.cshlp.org
Gene duplication is widely believed to facilitate adaptation, but unambiguous evidence for
this hypothesis has been found in only a small number of cases. Although gene duplication …

How natural genetic variation shapes behavior

N Niepoth, A Bendesky - Annual review of genomics and human …, 2020 - annualreviews.org
Nervous systems allow animals to acutely respond and behaviorally adapt to changes and
recurring patterns in their environment at multiple timescales—from milliseconds to years …

Massive losses of taste receptor genes in toothed and baleen whales

P Feng, J Zheng, SJ Rossiter, D Wang… - Genome biology and …, 2014 - academic.oup.com
Taste receptor genes are functionally important in animals, with a surprising exception in the
bottlenose dolphin, which shows extensive losses of sweet, umami, and bitter taste receptor …