Validity of low-contrast letter acuity as a visual performance outcome measure for multiple sclerosis

LJ Balcer, J Raynowska, R Nolan… - Multiple Sclerosis …, 2017‏ - journals.sagepub.com
Low-contrast letter acuity (LCLA) has emerged as the leading outcome measure to assess
visual disability in multiple sclerosis (MS) research. As visual dysfunction is one of the most …

Retinal ganglion cell analysis in multiple sclerosis and optic neuritis: a systematic review and meta-analysis

J Britze, G Pihl-Jensen, JL Frederiksen - Journal of neurology, 2017‏ - Springer
The aim of this study was to summarise existing findings regarding optical coherence
tomography (OCT) measurements of ganglion cell layer (GCL) alterations in optic neuritis …

Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

S Schippling, LJ Balk, F Costello… - Multiple sclerosis …, 2015‏ - journals.sagepub.com
Background: Retinal optical coherence tomography (OCT) permits quantification of retinal
layer atrophy relevant to assessment of neurodegeneration in multiple sclerosis (MS) …

Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study

S Saidha, ES Sotirchos, MA Ibrahim… - The Lancet …, 2012‏ - thelancet.com
Background Microcystic macular oedema (MMO) of the retinal inner nuclear layer (INL) has
been identified in patients with multiple sclerosis (MS) by use of optical coherence …

Active MS is associated with accelerated retinal ganglion cell/inner plexiform layer thinning

JN Ratchford, S Saidha, ES Sotirchos, JA Oh… - Neurology, 2013‏ - neurology.org
Objective: To determine the effect of clinical and radiologic disease activity on the rate of
thinning of the ganglion cell/inner plexiform (GCIP) layer and the retinal nerve fiber layer in …

Relationships between retinal axonal and neuronal measures and global central nervous system pathology in multiple sclerosis

S Saidha, ES Sotirchos, J Oh, SB Syc, MA Seigo… - JAMA …, 2013‏ - jamanetwork.com
Objective To determine the relationships between conventional and segmentation-derived
optical coherence tomography (OCT) retinal layer thickness measures with intracranial …

Normative reference ranges for the retinal nerve fiber layer, macula, and retinal layer thicknesses in children

SE Yanni, J Wang, CS Cheng, KI Locke, Y Wen… - American journal of …, 2013‏ - Elsevier
PURPOSE: To establish a normative database of peripapillary retinal nerve fiber layer
(RNFL) thickness, macular thickness, and retinal layer thickness in healthy North American …

Distribution of retinal layer atrophy in patients with Parkinson disease and association with disease severity and duration

E Garcia-Martin, JM Larrosa, V Polo, M Satue… - American journal of …, 2014‏ - Elsevier
Purpose To evaluate the thickness of the 10 retinal layers in the paramacular area of
Parkinson disease patients using a new segmentation technology of optical coherence …

Retinal ganglion cell and inner plexiform layer thinning in clinically isolated syndrome

T Oberwahrenbrock, M Ringelstein… - Multiple Sclerosis …, 2013‏ - journals.sagepub.com
Background: Axonal and neuronal damage are widely accepted as key events in the
disease course of multiple sclerosis. However, it has been unclear to date at which stage in …

Retinal pathology as biomarker for cognitive impairment and Alzheimer's disease

MK Ikram, CY Cheung, TY Wong… - Journal of Neurology …, 2012‏ - jnnp.bmj.com
Alzheimer's disease (AD) is the most common cause of dementia. Furthermore, over the last
few decades, there has been a shift towards identifying earlier stages of AD, which include …