Particle design via spherical agglomeration: A critical review of controlling parameters, rate processes and modelling
Particle design via spherical agglomeration is a size enlargement technique used in various
bulk and fine chemical industries, with recent interest extending into pharmaceuticals, in …
bulk and fine chemical industries, with recent interest extending into pharmaceuticals, in …
Spherical crystallization of drugs
B Kovačič, F Vrečer, O Planinšek - Acta pharmaceutica, 2012 - sciendo.com
Spherical crystallization of drugs is the process of obtaining larger particles by
agglomeration during crystallization. The most common techniques used to obtain such …
agglomeration during crystallization. The most common techniques used to obtain such …
Design of the spherical agglomerate size in crystallization by develo** a two‐step bridging mechanism and the model
Spherical agglomeration technology can produce high‐performance spherical particles in a
single crystallization unit, although it is still challenging to control the particle size and …
single crystallization unit, although it is still challenging to control the particle size and …
Spherical agglomerates of lactose with enhanced mechanical properties
D Lamešić, O Planinšek, Z Lavrič, I Ilić - International journal of …, 2017 - Elsevier
The aim of this study was to prepare spherical agglomerates of lactose and to evaluate their
physicochemical properties, flow properties, particle friability and compaction properties …
physicochemical properties, flow properties, particle friability and compaction properties …
Further understanding of agglomeration mechanisms in spherical crystallization systems: benzoic acid case study
Spherical crystallization is a particle size enlargement technique that can provide significant
process and micromeritic benefits to the production of active pharmaceutical ingredients. To …
process and micromeritic benefits to the production of active pharmaceutical ingredients. To …
Continuous spherical crystallization of lysozyme in an oscillatory baffled crystallizer using emulsion solvent diffusion in droplets
Continuous protein crystallization is a cost-effective alternative to traditional
chromatographic purification techniques. However, proteins characteristically have slow …
chromatographic purification techniques. However, proteins characteristically have slow …
Crystal engineering for enhanced solubility and bioavailability of poorly soluble drugs
Background: Crystal engineering is dealing with the creation of new structures and new
properties in drug molecules through inter-molecular interactions. Researchers of …
properties in drug molecules through inter-molecular interactions. Researchers of …
Preparation and Characterization of Co-Grinded Mixtures of Aceclofenac and Neusilin US2 for Dissolution Enhancement of Aceclofenac
AH Vadher, JR Parikh, RH Parikh, AB Solanki - Aaps Pharmscitech, 2009 - Springer
The present study was carried out with a view to enhance the dissolution of poorly water-
soluble BCS-class II drug aceclofenac by co-grinding with novel porous carrier Neusilin US …
soluble BCS-class II drug aceclofenac by co-grinding with novel porous carrier Neusilin US …
A top-down technique to improve the solubility and bioavailability of aceclofenac: in vitro and in vivo studies
R Narayan, A Pednekar, D Bhuyan… - International journal …, 2017 - Taylor & Francis
The aim of the present work was to tackle the solubility issue of a biopharmaceutics
classification system (BCS)-II drug, aceclofenac. Although a number of attempts to increase …
classification system (BCS)-II drug, aceclofenac. Although a number of attempts to increase …
Chitosan cocrystals embedded alginate beads for enhancing the solubility and bioavailability of aceclofenac
Enhanced oral bioavailability of aceclofenac has been achieved using chitosan cocrystals of
aceclofenac and its entrapment into alginate matrix a super saturated drug delivery system …
aceclofenac and its entrapment into alginate matrix a super saturated drug delivery system …