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The horizon of materiobiology: a perspective on material-guided cell behaviors and tissue engineering
Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …
How multiscale curvature couples forces to cellular functions
Among the physicochemical cues in the cellular microenvironment that orchestrate cell
processes, the different levels of curvature in the extracellular matrix and intrinsic to the …
processes, the different levels of curvature in the extracellular matrix and intrinsic to the …
Surface curvature differentially regulates stem cell migration and differentiation via altered attachment morphology and nuclear deformation
Signals from the microenvironment around a cell are known to influence cell behavior.
Material properties, such as biochemical composition and substrate stiffness, are today …
Material properties, such as biochemical composition and substrate stiffness, are today …
Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers
Piezo channels transduce mechanical stimuli into electrical and chemical signals to
powerfully influence development, tissue homeostasis, and regeneration. Studies on Piezo1 …
powerfully influence development, tissue homeostasis, and regeneration. Studies on Piezo1 …
Geometric cues for directing the differentiation of mesenchymal stem cells
Significant efforts have been directed to understanding the factors that influence the lineage
commitment of stem cells. This paper demonstrates that cell shape, independent of soluble …
commitment of stem cells. This paper demonstrates that cell shape, independent of soluble …
Self-assembled monolayers of thiolates on metals as a form of nanotechnology
Nanoscience includes the study of objects and systems in which at least one dimension is 1-
100 nm. The objects studied in this range of sizes are larger than atoms and small …
100 nm. The objects studied in this range of sizes are larger than atoms and small …
Environmental sensing through focal adhesions
Recent progress in the design and application of artificial cellular microenvironments and
nanoenvironments has revealed the extraordinary ability of cells to adjust their cytoskeletal …
nanoenvironments has revealed the extraordinary ability of cells to adjust their cytoskeletal …
Quantifying cell-generated mechanical forces within living embryonic tissues
Cell-generated mechanical forces play a critical role during tissue morphogenesis and
organ formation in the embryo. Little is known about how these forces shape embryonic …
organ formation in the embryo. Little is known about how these forces shape embryonic …
Innovative tools for mechanobiology: unraveling outside-in and inside-out mechanotransduction
Cells and tissues can sense and react to the modifications of the physico-chemical
properties of the extracellular environment (ECM) through integrin-based adhesion sites and …
properties of the extracellular environment (ECM) through integrin-based adhesion sites and …
Spatial coordination between cell and nuclear shape within micropatterned endothelial cells
Growing evidence suggests that cytoplasmic actin filaments are essential factors in the
modulation of nuclear shape and function. However, the mechanistic understanding of the …
modulation of nuclear shape and function. However, the mechanistic understanding of the …