Identification of intrinsic disorder in proteins relies in large part on computational predictors,
which demands that their accuracy should be high. Since intrinsic disorder carries out a …

Cellular processes often depend on interactions between proteins and the formation of
macromolecular complexes. The impairment of such interactions can lead to deregulation of …

Recent years witnessed increased interest in intrinsically disordered proteins and regions.
These proteins and regions are abundant and possess unique structural features and a …

Motivation: Redundant protein sequences in biological databases hinder sequence
similarity searches and make interpretation of search results difficult. Clustering of protein …

Motivation: All residues in a protein are not equally important. Some are essential for the
proper structure and function of the protein, whereas others can be readily replaced …

Identifying a protein's functional sites is an important step towards characterizing its
molecular function. Numerous structure-and sequence-based methods have been …

Virus infection triggers a plethora of defence reactions in plants to incapacitate the intruder.
Viruses, in turn, have added additional functions to their genes so that they acquire …

Understanding intracellular phase separation is crucial for deciphering transcriptional
control, cell fate transitions, and disease mechanisms. However, the key residues, which …

We present DescribePROT, the database of predicted amino acid-level descriptors of
structure and function of proteins. DescribePROT delivers a comprehensive collection of 13 …

Intrinsically disordered proteins (IDPs) participate in many biological processes by
interacting with other proteins, including the regulation of transcription, translation, and the …