Chimeric antigen receptor T (CAR-T) cell therapy is a promising and precise targeted
therapy for cancer that has demonstrated notable potential in clinical applications. However …

There is a rich history of cancer treatments which provides a number of important lessons for
present and future cancer therapies. We outline this history by looking in the past, reviewing …

Over the last decade, the composition of the gut microbiota has been found to correlate with
the outcomes of cancer patients treated with immunotherapy. Accumulating evidence points …

Chimeric antigen receptor T cell denoted as CAR-T therapy has realized incredible
therapeutic advancements for B cell malignancy treatment. However, its therapeutic validity …

As natural living substances, microorganisms have emerged as useful resources in
medicine for creating microbe-material hybrids ranging from nano to macro dimensions. The …

As the limitations of cancer immunotherapy become increasingly apparent, there is
considerable anticipation regarding the utilization of biological tools to enhance treatment …

In recent years, advancements in microbial sequencing technology have sparked an
increasing interest in the bacteria residing within solid tumors and its distribution and …

Cancer is generally defined as a disease of aging. With aging, the composition, diversity and
functional characteristics of the gut microbiota occur changes, with a decline of beneficial …

Highlights•Bacteria can act as engineered live therapeutics for tumor targeting.•New
strategies are needed to improve tumor colonization without causing widespread …

Conspectus Cells, particularly living cells, serve as natural carriers of bioactive substances.
Their inherent low immunogenicity and multifunctionality have garnered significant attention …