Lung cancer screening

SJ Adams, E Stone, DR Baldwin, R Vliegenthart, P Lee… - The Lancet, 2023 - thelancet.com
Randomised controlled trials, including the National Lung Screening Trial (NLST) and the
NELSON trial, have shown reduced mortality with lung cancer screening with low-dose CT …

Lung cancer LDCT screening and mortality reduction—evidence, pitfalls and future perspectives

M Oudkerk, SY Liu, MA Heuvelmans… - Nature reviews Clinical …, 2021 - nature.com
In the past decade, the introduction of molecularly targeted agents and immune-checkpoint
inhibitors has led to improved survival outcomes for patients with advanced-stage lung …

Risk-Based lung cancer screening: A systematic review

I Toumazis, M Bastani, SS Han, SK Plevritis - Lung cancer, 2020 - Elsevier
Lung cancer remains the leading cause of cancer related deaths worldwide. Lung cancer
screening using low-dose computed tomography (LDCT) has been shown to reduce lung …

Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis

JK Field, D Vulkan, MPA Davies… - The lancet regional …, 2021 - thelancet.com
Background The NLST reported a significant 20% reduction in lung cancer mortality with
three annual low-dose CT (LDCT) screens and the Dutch-Belgian NELSON trial indicates a …

Personalising lung cancer screening: An overview of risk‐stratification opportunities and challenges

K Ten Haaf, CM van der Aalst… - … journal of cancer, 2021 - Wiley Online Library
Randomised clinical trials have shown the efficacy of computed tomography lung cancer
screening, initiating discussions on whether and how to implement population‐based …

[HTML][HTML] Implementing lung cancer screening in Europe: taking a systems approach

S Wait, A Alvarez-Rosete, T Osama, D Bancroft… - JTO Clinical and …, 2022 - Elsevier
Lung cancer is the leading cause of cancer death in Europe. Screening by means of low-
dose computed tomography (LDCT) can shift detection to an earlier stage and reduce lung …

Analysis of the baseline performance of five UK lung cancer screening programmes

H Balata, M Ruparel, E O'Dowd, M Ledson, JK Field… - Lung Cancer, 2021 - Elsevier
Abstract Introduction Low-dose CT (LDCT) screening reduces lung cancer specific mortality.
Several countries, including the UK, are evaluating the clinical impact and cost-effectiveness …

Recommendations for implementing lung cancer screening with low-dose computed tomography in Europe

G Veronesi, DR Baldwin, CI Henschke, S Ghislandi… - Cancers, 2020 - mdpi.com
Lung cancer screening (LCS) with low-dose computed tomography (LDCT) was
demonstrated in the National Lung Screening Trial (NLST) to reduce mortality from the …

The challenges of implementing low-dose computed tomography for lung cancer screening in low-and middle-income countries

E Edelman Saul, RB Guerra, M Edelman Saul… - Nature Cancer, 2020 - nature.com
Lung cancer accounts for an alarming human and economic burden in low-and middle-
income countries (LMICs). Recent landmark trials from high-income countries (HICs) by …

Comparative performance of lung cancer risk models to define lung screening eligibility in the United Kingdom

HA Robbins, K Alcala, AJ Swerdlow… - British journal of …, 2021 - nature.com
Abstract Background The National Health Service England (NHS) classifies individuals as
eligible for lung cancer screening using two risk prediction models, PLCOm2012 and …