Thiazolidinone is a biologically important five‐membered heterocyclic ring having almost all
types of biological activities. This review covers various types of thiazolidinones, such as 2 …

Heterocyclic scaffolds are playing the important role in drug discovery and development.
Currently many heterocyclic scaffolds like thiazole, thiazolidinone or thiazolidinedione have …

Abstract In this work, iminothiazolidin-4-one derivatives were explored as selective GSK-3β
inhibitors. Molecular docking analysis was carried to design a series of compounds, which …

New series of isoxazole derivatives were synthesized and evaluated for in vitro antitumor
activity against HepG2, MCF-7 and HCT-116 cancer cells. Results showed that 4b and 25a …

The present research was aimed at the synthesis and screening of 35 novel 2-(substituted
phenyl imino)-5-benzylidene-4-thiazolidinones having different substitutions at imino phenyl …

Thiazolidinone (TZD) derivatives, especially those containing a 1, 3‐thiazolidine‐4‐one
core, are highly valued in drug design due to their broad spectrum of biological activities …

ABSTRACT A series of novel 2-(3-(2-(1, 3-dioxoisoindolin-2-yl) acetamido)-4-oxo-2-
phenylthiazolidin-5-yl) acetic acid (5a-l) have been synthesized by cyclocondensation of N …

Aromataz enzimi, temel bir sitokrom P450 alt tipidir. Sırasıyla (CYP19) ve (CYP51) alt tipleri
ile insanda androjenden östrojen biyosentezindeki hız sınırlayıcı adımdan ve mantarlarda …

A series of novel 2-imino-4-thiazolidinone (5a-p) derivatives was synthesized and evaluated
for their cytotoxic activity against glioma (C6) cancer cell line, on the other hand, this work …

Heterocyclic compounds, having atoms other than carbon in the ring, have long been
proven to have vivid biological activities. The biological activities of heterocyclic rings, such …