[HTML][HTML] Genomic and non-genomic actions of glucocorticoids on adipose tissue lipid metabolism

N Mir, SA Chin, MC Riddell, JL Beaudry - International journal of …, 2021 - mdpi.com
Glucocorticoids (GCs) are hormones that aid the body under stress by regulating glucose
and free fatty acids. GCs maintain energy homeostasis in multiple tissues, including those in …

G allele of the rs1801282 polymorphism in PPARγ gene confers an increased risk of obesity and hypercholesterolemia, while T allele of the rs3856806 polymorphism …

S Li, C He, H Nie, Q Pang, R Wang, Z Zeng… - Frontiers in …, 2022 - frontiersin.org
Background The relationships between the rs1801282 and rs3856806 polymorphisms in
nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) gene and …

PPARγ Gene polymorphisms, metabolic disorders, and coronary artery disease

Y Song, S Li, C He - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Being activated by endogenous and exogenous ligands, nuclear receptor peroxisome
proliferator-activated receptor gamma (PPARγ) enhances insulin sensitivity, promotes …

Effects of PPARG and PPARGC1A gene polymorphisms on obesity markers

C Muntean, MO Sasaran, A Crisan… - Frontiers in Public …, 2022 - frontiersin.org
Pediatric obesity presents a multifactorial etiology, which involves genetic traits as well,
including single nucleotide polymorphisms. The aim of the study is to investigate the …

The Pro12Ala Polymorphism in the Peroxisome Proliferator-Activated Receptor Gamma-2 Gene (PPARγ2) Is Associated with Increased Risk of Coronary Artery …

Z Wu, Y Lou, W **, Y Liu, L Lu, G Lu - PLoS One, 2012 - journals.plos.org
Background Contradictory results have been reported regarding the association between
Pro12Ala polymorphism of PPARγ2 and coronary artery disease (CAD). We sought to …

Impact of the C1431T polymorphism of the peroxisome proliferator activated receptor-gamma (PPAR-γ) gene on fasted serum lipid levels in patients with coronary …

M Oladi, M Nohtani, A Avan, SR Mirhafez… - Annals of Nutrition and …, 2015 - karger.com
Abstract Background/Aims: The C1431T polymorphism of peroxisome proliferator activated
receptor-γ (PPAR-γ) gene is related to diabetes and metabolic-syndrome. However, studies …

Is the mouse a good model of human PPARγ-related metabolic diseases?

A Pap, I Cuaranta-Monroy, M Peloquin… - International journal of …, 2016 - mdpi.com
With the increasing number of patients affected with metabolic diseases such as type 2
diabetes, obesity, atherosclerosis and insulin resistance, academic researchers and …

Association between peroxisome proliferator-activated receptor-alpha, delta, and gamma polymorphisms and risk of coronary heart disease: A case–control study and …

Y Qian, P Li, J Zhang, Y Shi, K Chen, J Yang, Y Wu… - Medicine, 2016 - journals.lww.com
Objectives: Risk of coronary heart disease (CHD) has been suggested to be associated with
polymorphisms of peroxisome proliferator-activated receptors (PPARs), while the results …

PPARA, PPARD and PPARG gene polymorphisms in patients with unstable angina

A Maciejewska-Skrendo, A Pawlik, M Sawczuk, M Rać… - Gene, 2019 - Elsevier
Background Peroxisome proliferator-activated receptors (PPARs) include the nuclear
receptor superfamily of ligand-activated transcription factors involved in several metabolic …

Association between PPARG genetic polymorphisms and ischemic stroke risk in a northern Chinese Han population: a case-control study

YZ Wang, HY Zhang, F Liu, L Li… - Neural Regeneration …, 2019 - journals.lww.com
Two common polymorphisms of the peroxisome proliferator-activated receptor gamma
(PPARG) gene, rs1801282 and rs3856806, may be important candidate gene loci affecting …