All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

The 4th edition of the World Health Organization (WHO) classification of endocrine tumors
has been recently released. In this new edition, major changes are recommended in several …

Background Pituitary tumours are common and easily treated by surgery or medical
treatment in most cases. However, a small subset of pituitary tumours does not respond to …

This review focuses on discussing the main changes on the upcoming fourth edition of the
WHO Classification of Tumors of the Pituitary Gland emphasizing histopathological and …

Adenohypophyseal tumors, which were recently renamed pituitary neuroendocrine tumors
(PitNET), are mostly benign, but may present various behaviors: invasive,“aggressive” and …

Pituitary adenomas are currently classified by histological, immunocytochemical and
numerous ultrastructural characteristics lacking unequivocal prognostic correlations. We …

The WHO categorizes pituitary tumours as typical adenomas, atypical adenomas and
pituitary carcinomas, with typical adenomas constituting the major class. However, the WHO …

Background Most pituitary neuroendocrine tumors (PitNETs) show benign behavior, but a
substantial number are invasive, recur, or resist medical treatment. Based on a retrospective …

Pituitary adenomas are common intracranial tumors that are mainly considered as benign.
Rarely, these tumors can exhibit an aggressive behavior, characterized by gross invasion of …

Context Pituitary carcinoma is a rare and aggressive malignancy with a poor prognosis and
few effective treatment options. Case A 35-year-old woman presented with an aggressive …