The new WHO classification of adrenal cortical proliferations reflects translational advances
in the fields of endocrine pathology, oncology and molecular biology. By adopting a …

Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

Objective: To develop clinical practice guidelines for the management of patients with
primary aldosteronism. Participants: The Task Force included a chair, selected by the …

An adrenal incidentaloma is now established as a common endocrine diagnosis that
requires a multidisciplinary approach for effective management. The majority of patients can …

The sodium and potassium gradients across the plasma membrane are used by animal cells
for numerous processes, and the range of demands requires that the responsible ion pump …

Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …

Primary aldosteronism (PA), the most common form of secondary hypertension, can be
either surgically cured or treated with targeted pharmacotherapy. PA is frequently …

Blockers of the renin–angiotensin–aldosterone system (RAAS), that is, renin inhibitors,
angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists …

Given the importance of Africa to studies of human origins and disease susceptibility,
detailed characterization of African genetic diversity is needed. The African Genome …

Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …