Characterization of a hepatitis outbreak in children, 2021 to 2022

EC Alexander, A Deep - JAMA network open, 2022 - jamanetwork.com
Importance After a cluster of pediatric cases of hepatitis of unknown etiology were identified
in Scotland in March 2022, the World Health Organization published an outbreak alert, and …

Cell therapy in end-stage liver disease: replace and remodel

XH Hu, L Chen, H Wu, YB Tang, QM Zheng… - Stem Cell Research & …, 2023 - Springer
Liver disease is prevalent worldwide. When it reaches the end stage, mortality rises to 50%
or more. Although liver transplantation has emerged as the most efficient treatment for end …

Liver support systems and liver transplantation in acute liver failure

FS Larsen, F Saliba - Liver International, 2023 - Wiley Online Library
Acute liver failure (ALF) results in a multitude of complications that result in multi‐organ
failure. This review focuses on the pathophysiological processes and how to manage with …

Continuous renal replacement therapy in neonates and children: what does the pediatrician need to know? An overview from the Critical Care Nephrology Section of …

G Cortina, M Daverio, D Demirkol… - European Journal of …, 2024 - Springer
Continuous renal replacement therapy (CRRT) is the preferred method for renal support in
critically ill and hemodynamically unstable children in the pediatric intensive care unit …

Safety and efficacy of continuous renal replacement therapy for children less than 10 kg using standard adult machines

M Kedarnath, EC Alexander, A Deep - European Journal of Pediatrics, 2023 - Springer
Abstract Continuous Renal Replacement Therapy (CRRT) machines are used off-label in
patients less than 20 kg. Infant and neonates-dedicated CRRT machines are making their …

Critical care management of acute liver failure

SS Sehrawat, M Premkumar - Indian Journal of Gastroenterology, 2024 - Springer
The management of acute liver failure (ALF) in modern hepatology intensive care units (ICU)
has improved patient outcomes. Critical care management of hepatic encephalopathy …

Intraoperative kidney replacement therapy in acute liver failure

D Henderson, A Gupta, S Menon, A Deep - Pediatric Nephrology, 2024 - Springer
Paediatric acute liver failure (PALF) is often characterised by its rapidity of onset and
potential for significant morbidity and even mortality. Patients often develop multiorgan …

Epoprostenol (Prostacyclin Analog) as a sole anticoagulant in continuous renal replacement therapy for critically ill children with liver disease: Single-center …

A Deep, EC Alexander, A Khatri, N Kumari… - Pediatric Critical Care …, 2024 - journals.lww.com
OBJECTIVES: Despite deranged coagulation, children with liver disease undergoing
continuous renal replacement therapy (CRRT) are prone to circuit clotting. Commonly used …

Intracellular Trafficking Defects in Congenital Intestinal and Hepatic Diseases

L Szabó, AR Pollio, GF Vogel - Traffic, 2024 - Wiley Online Library
Enterocytes and liver cells fulfill important metabolic and barrier functions and are
responsible for crucial vectorial secretive and absorptive processes. To date, genetic …

Value of extracorporeal artificial liver support in pediatric acute liver failure: A single-center experience of over 10 years

I Ocak - Frontiers in Pediatrics, 2023 - frontiersin.org
Purpose Acute liver failure (ALF) is a life-threatening disease characterized by rapid-onset
liver dysfunction, coagulopathy, and encephalopathy in patients without chronic liver …