Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …
Regulation and function of adult neurogenesis: from genes to cognition
JB Aimone, Y Li, SW Lee… - Physiological …, 2014 - journals.physiology.org
Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …
and potential impact on cognition but also to its localized vertical integration of different …
Adult-born dentate granule cells promote hippocampal population sparsity
The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly,
the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan …
the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan …
Physiological properties and behavioral correlates of hippocampal granule cells and mossy cells
The hippocampal dentate gyrus is often viewed as a segregator of upstream information.
Physiological support for such function has been hampered by a lack of well-defined …
Physiological support for such function has been hampered by a lack of well-defined …
The mechanisms for pattern completion and pattern separation in the hippocampus
ET Rolls - Frontiers in systems neuroscience, 2013 - frontiersin.org
The mechanisms for pattern completion and pattern separation are described in the context
of a theory of hippocampal function in which the hippocampal CA3 system operates as a …
of a theory of hippocampal function in which the hippocampal CA3 system operates as a …
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
The integration of adult-born neurons into the circuitry of the adult hippocampus suggests an
important role for adult hippocampal neurogenesis in learning and memory, but its specific …
important role for adult hippocampal neurogenesis in learning and memory, but its specific …
Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders
Although an influence of adult neurogenesis in mediating some of the effects of
antidepressants has received considerable attention in recent years, much less is known …
antidepressants has received considerable attention in recent years, much less is known …
A computational theory of hippocampal function, and tests of the theory: new developments
The aims of the paper are to update Rolls' quantitative computational theory of hippocampal
function and the predictions it makes about the different subregions (dentate gyrus, CA3 and …
function and the predictions it makes about the different subregions (dentate gyrus, CA3 and …
Synaptic mechanisms of pattern completion in the hippocampal CA3 network
The hippocampal CA3 region plays a key role in learning and memory. Recurrent CA3–CA3
synapses are thought to be the subcellular substrate of pattern completion. However, the …
synapses are thought to be the subcellular substrate of pattern completion. However, the …
Pyramidal cell-interneuron circuit architecture and dynamics in hippocampal networks
Excitatory control of inhibitory neurons is poorly understood due to the difficulty of studying
synaptic connectivity in vivo. We inferred such connectivity through analysis of spike timing …
synaptic connectivity in vivo. We inferred such connectivity through analysis of spike timing …