Massive image-based single-cell profiling reveals high levels of circulating platelet aggregates in patients with COVID-19
A characteristic clinical feature of COVID-19 is the frequent incidence of microvascular
thrombosis. In fact, COVID-19 autopsy reports have shown widespread thrombotic …
thrombosis. In fact, COVID-19 autopsy reports have shown widespread thrombotic …
Deep imaging flow cytometry
Imaging flow cytometry (IFC) has become a powerful tool for diverse biomedical applications
by virtue of its ability to image single cells in a high-throughput manner. However, there …
by virtue of its ability to image single cells in a high-throughput manner. However, there …
Revolutionizing microfluidics with artificial intelligence: a new dawn for lab-on-a-chip technologies
10.1039/D2LC00813K). 1–5 This groundbreaking blend of physical manipulation and digital
intelligence signifies a crucial turning point for labon-a-chip technologies, marking the onset …
intelligence signifies a crucial turning point for labon-a-chip technologies, marking the onset …
Targeting biophysical cues to address platelet storage lesions
S Wang, Q Liu, L Cheng, L Wang, F Xu, C Yao - Acta Biomaterialia, 2022 - Elsevier
Platelets play vital roles in vascular repair, especially in primary hemostasis, and have been
widely used in transfusion to prevent bleeding or manage active bleeding. Recently …
widely used in transfusion to prevent bleeding or manage active bleeding. Recently …
Studying the efficacy of antiplatelet drugs on atherosclerosis by optofluidic imaging on a chip
Vascular stenosis caused by atherosclerosis instigates activation and aggregation of
platelets, eventually resulting in thrombus formation. Although antiplatelet drugs are …
platelets, eventually resulting in thrombus formation. Although antiplatelet drugs are …
[HTML][HTML] Advancing Platelet Research Through Live-Cell Imaging: Challenges, Techniques, and Insights
YY Tan, J Liu, QP Su - Sensors, 2025 - mdpi.com
Platelet cells are essential to maintain haemostasis and play a critical role in thrombosis.
They swiftly respond to vascular injury by adhering to damaged vessel surfaces, activating …
They swiftly respond to vascular injury by adhering to damaged vessel surfaces, activating …
[PDF][PDF] Label-free in-vivo classification and tracking of red blood cells and platelets using Dynamic-YOLOv4 network
C Guan, B He, H Zhang, S Yang, Y Xu… - Journal of Innovative …, 2024 - researching.cn
2450009-1 experimental model, the D-YOLOv4 method achieved average precisions (APs)
of 0.90 for RBCs and 0.64 for thrombocytes (similar to platelets in mammals), resulting in an …
of 0.90 for RBCs and 0.64 for thrombocytes (similar to platelets in mammals), resulting in an …
Intelligent sort‐timing prediction for image‐activated cell sorting
Intelligent image‐activated cell sorting (iIACS) has enabled high‐throughput image‐based
sorting of single cells with artificial intelligence (AI) algorithms. This AI‐on‐a‐chip technology …
sorting of single cells with artificial intelligence (AI) algorithms. This AI‐on‐a‐chip technology …
Understanding stenosis-induced platelet aggregation on a chip by high-speed optical imaging
Vascular stenosis is a pathological hallmark of atherosclerosis, the leading cause of
cardiovascular diseases such as stroke and myocardial infarction. While stenosis-induced …
cardiovascular diseases such as stroke and myocardial infarction. While stenosis-induced …
Real‐time intelligent classification of COVID‐19 and thrombosis via massive image‐based analysis of platelet aggregates
Microvascular thrombosis is a typical symptom of COVID‐19 and shows similarities to
thrombosis. Using a microfluidic imaging flow cytometer, we measured the blood of 181 …
thrombosis. Using a microfluidic imaging flow cytometer, we measured the blood of 181 …