Recent advances in stationary phases and understanding of retention in hydrophilic interaction chromatography. A review

P Jandera, P Janás - Analytica Chimica Acta, 2017 - Elsevier
Hydrophilic interaction chromatography (HILIC) is a rapidly develo** liquid
chromatography mode suitable for separation of strongly or moderately polar samples on …

Understanding and manipulating the separation in hydrophilic interaction liquid chromatography

DV McCalley - Journal of chromatography A, 2017 - Elsevier
Hydrophilic interaction liquid chromatography (HILIC) has emerged as a valuable
complimentary technique to reversed-phase (RP), being especially suited for the analysis of …

HILIC‐MS for metabolomics: An attractive and complementary approach to RPLC‐MS

DQ Tang, L Zou, XX Yin, CN Ong - Mass spectrometry reviews, 2016 - Wiley Online Library
Hydrophilic interaction chromatography (HILIC) is an emerging separation mode of liquid
chromatography (LC). Using highly hydrophilic stationary phases capable of retaining …

Main interactions and influences of the chromatographic parameters in HILIC separations

G Greco, T Letzel - Journal of chromatographic science, 2013 - academic.oup.com
Hydrophilic interaction liquid chromatography (HILIC) is a popular technique for the
separation of polar compounds, which are poorly retained by reversed-phase liquid …

Hydrophilic interaction chromatography

MR Gama, RG da Costa Silva, CH Collins… - TrAC Trends in …, 2012 - Elsevier
In the early 1990s, hydrophilic interaction (liquid) chromatography (HILIC) emerged as a
new separation method. HILIC is becoming increasingly popular for the separation of polar …

RepoRT: a comprehensive repository for small molecule retention times

F Kretschmer, EM Harrieder, MA Hoffmann, S Böcker… - Nature …, 2024 - nature.com
Liquid chromatography (LC) is fre-quently used to separate metabolites and other small
molecules. Retention time is the time required for a particular molecule to pass through the …

Advances in hydrophilic nanomaterials for glycoproteomics

N Sun, H Wu, H Chen, X Shen, C Deng - Chemical Communications, 2019 - pubs.rsc.org
Owing to the formidable challenge posed by microheterogeneities in glycosylation sites,
macroheterogeneity of the modification number of glycans, and low abundance and …

Analysis of mobile chemicals in the aquatic environment—current capabilities, limitations and future perspectives

D Zahn, IJ Neuwald, TP Knepper - Analytical and Bioanalytical Chemistry, 2020 - Springer
Persistent and mobile water contaminants are rapidly develo** into a focal point of
environmental chemistry and chemical regulation. Their defining parameter that sets them …

[HTML][HTML] Effect of salts on retention in hydrophilic interaction chromatography

AJ Alpert - Journal of Chromatography a, 2018 - Elsevier
There is a widespread belief that salts promote retention of solutes in hydrophilic interaction
chromatography (HILIC) by expanding the volume of the immobilized layer of water on the …

Chemometric-assisted method development in hydrophilic interaction liquid chromatography: a review

M Taraji, PR Haddad, RIJ Amos, M Talebi, R Szucs… - Analytica chimica …, 2018 - Elsevier
With an enormous growth in the application of hydrophilic interaction liquid chromatography
(HILIC), there has also been significant progress in HILIC method development. HILIC is a …