Lipid nanoparticles (LNPs) have been recognized as efficient vehicles to transport a large
variety of therapeutics. Currently in the spotlight as important constituents of the COVID-19 …

As the mainstay in the treatment of various cancers, chemotherapy plays a vital role, but still
faces many challenges, such as poor tumour selectivity and multidrug resistance (MDR) …

It is well-known that aqueous dispersions of phospholipids spontaneously assemble into
bilayer structures. These structures have numerous applications across chemistry and …

Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Liposomes are emerging cargoes for bioactive delivery owing to their widely accepted
biocompatible and biodegradable nature. It is always a challenge to control the release of …

Circulating microRNAs (c-microRNAs, c-miRNAs), which are present in almost all biological
fluids, are promising sensitive biomarkers for various diseases (oncological and …

RNA interference (RNAi)-based technologies offer an attractive strategy for the sequence-
specific silencing of disease-causing genes. The application of small interfering (si) RNAs as …

The paradigm of using nanoparticulate pharmaceutical carriers has been well established
over the past decade, both in pharmaceutical research and in the clinical setting. Drug …

Gene silencing by RNA interference represents a promising therapeutic approach. The
development of carriers, eg, polymers, lipids, peptides, antibodies, aptamers, small …

Abstract Lipid-based colloidal particles have been extensively studied as systemic gene
delivery carriers. The topic that we would like to emphasize is the formulation/assembly of …