Diversity and evolution of the animal virome

E Harvey, EC Holmes - Nature Reviews Microbiology, 2022 - nature.com
The COVID-19 pandemic has given the study of virus evolution and ecology new relevance.
Although viruses were first identified more than a century ago, we likely know less about …

Bacteriophages of the human gut: the “known unknown” of the microbiome

AN Shkoporov, C Hill - Cell host & microbe, 2019 - cell.com
The human gut microbiome is a dense and taxonomically diverse consortium of
microorganisms. While the bacterial components of the microbiome have received …

Metabolic and biogeochemical consequences of viral infection in aquatic ecosystems

AE Zimmerman, C Howard-Varona… - Nature Reviews …, 2020 - nature.com
Ecosystems are controlled by 'bottom-up'(resources) and 'top-down'(predation) forces. Viral
infection is now recognized as a ubiquitous top-down control of microbial growth across …

Translating phage therapy into the clinic: Recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth's biomes

S Roux, M Krupovic, RA Daly, AL Borges… - Nature …, 2019 - nature.com
Bacteriophages from the Inoviridae family (inoviruses) are characterized by their unique
morphology, genome content and infection cycle. One of the most striking features of …

Multiple origins of prokaryotic and eukaryotic single-stranded DNA viruses from bacterial and archaeal plasmids

D Kazlauskas, A Varsani, EV Koonin… - Nature …, 2019 - nature.com
Single-stranded (ss) DNA viruses are a major component of the earth virome. In particular,
the circular, Rep-encoding ssDNA (CRESS-DNA) viruses show high diversity and …

Global organization and proposed megataxonomy of the virus world

EV Koonin, VV Dolja, M Krupovic… - Microbiology and …, 2020 - Am Soc Microbiol
Viruses and mobile genetic elements are molecular parasites or symbionts that coevolve
with nearly all forms of cellular life. The route of virus replication and protein expression is …

[HTML][HTML] Metagenomics reshapes the concepts of RNA virus evolution by revealing extensive horizontal virus transfer

VV Dolja, EV Koonin - Virus research, 2018 - Elsevier
Virus metagenomics is a young research filed but it has already transformed our
understanding of virus diversity and evolution, and illuminated at a new level the …

Three families of Asgard archaeal viruses identified in metagenome-assembled genomes

S Medvedeva, J Sun, N Yutin, EV Koonin… - Nature …, 2022 - nature.com
Asgardarchaeota harbour many eukaryotic signature proteins and are widely considered to
represent the closest archaeal relatives of eukaryotes. Whether similarities between Asgard …

Genomes of six viruses that infect Asgard archaea from deep-sea sediments

IM Rambo, MV Langwig, P Leão, V De Anda… - Nature …, 2022 - nature.com
Asgard archaea are globally distributed prokaryotic microorganisms related to eukaryotes;
however, viruses that infect these organisms have not been described. Here, using …