Tutorial review on validation of liquid chromatography–mass spectrometry methods: Part I
This is the part I of a tutorial review intending to give an overview of the state of the art of
method validation in liquid chromatography mass spectrometry (LC–MS) and discuss …
method validation in liquid chromatography mass spectrometry (LC–MS) and discuss …
Pharmacokinetic and pharmacodynamic of bupropion: integrative overview of relevant clinical and forensic aspects
R Costa, NG Oliveira, RJ Dinis-Oliveira - Drug metabolism reviews, 2019 - Taylor & Francis
Bupropion is an atypical antidepressant of the aminoketone group, structurally related to
cathinone, associated with a wide interindividual variability. An extensive pharmacokinetic …
cathinone, associated with a wide interindividual variability. An extensive pharmacokinetic …
Recent developments and emerging trends of mass spectrometric methods in plant hormone analysis: a review
Plant hormones are naturally occurring small molecule compounds which are present at
trace amounts in plant. They play a pivotal role in the regulation of plant growth. The …
trace amounts in plant. They play a pivotal role in the regulation of plant growth. The …
A review of sample preparation methods for quantitation of small-molecule analytes in brain tissue by liquid chromatography tandem mass spectrometry (LC-MS/MS)
P Li, MG Bartlett - Analytical Methods, 2014 - pubs.rsc.org
Concentration measurements are one of the most important and fundamental approaches in
preclinical and clinical studies of small-molecule drugs, metabolites and biomarkers, since …
preclinical and clinical studies of small-molecule drugs, metabolites and biomarkers, since …
[HTML][HTML] Determination of bupropion and its impurities via a chaotropic chromatography method following analytical quality-by-design principles for method …
K Gkountanas, A Malenović, Y Dotsikas - Pharmaceuticals, 2022 - mdpi.com
A novel chaotropic chromatography method for the quantitative determination of bupropion
and its impurities, following analytical quality-by-design (AQbD) principles, is presented. The …
and its impurities, following analytical quality-by-design (AQbD) principles, is presented. The …
LC-MS/MS combined with in vivo microdialysis sampling from conscious rat striatum for simultaneous determination of active constituents of Yuanhu-Baizhi herb pair …
J Le, Z Lin, L Song, H Wang, Z Hong - Journal of Pharmaceutical and …, 2019 - Elsevier
Abstract The compatibility of Rhizoma Corydalis (Yuanhu, YH) and Radix Angelicae
dahuricae (Baizhi, BZ) as a herb pair Yuanhu-Baizhi (YB) can produce synergistic analgesic …
dahuricae (Baizhi, BZ) as a herb pair Yuanhu-Baizhi (YB) can produce synergistic analgesic …
UFLC–MS/MS method for simultaneous determination of six lignans of Schisandra chinensis (Turcz.) Baill. in normal and insomniac rats brain microdialysates and …
B Wei, Q Li, R Fan, D Su, X Ou, K Chen… - Journal of Mass …, 2013 - Wiley Online Library
Schisandra chinensis (Turcz.) Baill., a traditional Chinese medicine, has been clinically used
for the treatment of insomnia for centuries. The insomnia mechanism and the possible active …
for the treatment of insomnia for centuries. The insomnia mechanism and the possible active …
Effects of arecoline on hepatic cytochrome P450 activity and oxidative stress
X Run-mei, W Jun-jun, C **g-ya, S Li-juan… - The Journal of …, 2014 - jstage.jst.go.jp
Betel-quid use is associated with the risk of liver cirrhosis and hepatocellular carcinoma. The
aim of the present work was to evaluate the impact of arecoline on human hepatic …
aim of the present work was to evaluate the impact of arecoline on human hepatic …
Development of a rat plasma and brain extracellular fluid pharmacokinetic model for bupropion and hydroxybupropion based on microdialysis sampling, and …
TIFH Cremers, G Flik, JHA Folgering, H Rollema… - Drug Metabolism and …, 2016 - Elsevier
Administration of bupropion [(±)-2-(tert-butylamino)-1-(3-chlorophenyl) propan-1-one] and its
preformed active metabolite, hydroxybupropion [(±)-1-(3-chlorophenyl)-2-[(1-hydroxy-2 …
preformed active metabolite, hydroxybupropion [(±)-1-(3-chlorophenyl)-2-[(1-hydroxy-2 …
Sensitive, selective and rapid determination of bupropion and its major active metabolite, hydroxybupropion, in human plasma by LC‐MS/MS: application to a …
JM Parekh, DK Sutariya, RN Vaghela… - Biomedical …, 2012 - Wiley Online Library
ABSTRACT A sensitive, selective and rapid liquid chromatography tandem mass
spectrometry (LC‐MS/MS) method was developed for the simultaneous determination of …
spectrometry (LC‐MS/MS) method was developed for the simultaneous determination of …