Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Copper oxide nanoparticles: In vitro and in vivo toxicity, mechanisms of action and factors influencing their toxicology

H Sajjad, A Sajjad, RT Haya, MM Khan, M Zia - … and Physiology Part C …, 2023 - Elsevier
Abstract Copper oxide nanoparticles (CuO NPs) have received increasing interest due to
their distinctive properties, including small particle size, high surface area, and reactivity …

Size and surface charge characterization of nanoparticles with a salt gradient

MK Rasmussen, JN Pedersen, R Marie - Nature communications, 2020 - nature.com
Exosomes are nanometer-sized lipid vesicles present in liquid biopsies and used as
biomarkers for several diseases including cancer, Alzheimer's, and central nervous system …

Cellular uptake of nanoparticles: journey inside the cell

S Behzadi, V Serpooshan, W Tao, MA Hamaly… - Chemical society …, 2017 - pubs.rsc.org
Nanoscale materials are increasingly found in consumer goods, electronics, and
pharmaceuticals. While these particles interact with the body in myriad ways, their beneficial …

A repertoire of biomedical applications of noble metal nanoparticles

M Azharuddin, GH Zhu, D Das, E Ozgur… - Chemical …, 2019 - pubs.rsc.org
Noble metals comprise any of several metallic chemical elements that are outstandingly
resistant to corrosion and oxidation, even at elevated temperatures. This group is not strictly …

Surface modifications of nanoparticles for stability in biological fluids

L Guerrini, RA Alvarez-Puebla, N Pazos-Perez - Materials, 2018 - mdpi.com
Due to the high surface: volume ratio and the extraordinary properties arising from the
nanoscale (optical, electric, magnetic, etc.), nanoparticles (NPs) are excellent candidates for …

The effect of shape on cellular uptake of gold nanoparticles in the forms of stars, rods, and triangles

X **e, J Liao, X Shao, Q Li, Y Lin - Scientific reports, 2017 - nature.com
Gold nanomaterials have attracted considerable interest as vehicles for intracellular drug
delivery. In our study, we synthesized three different shapes of methylpolyethylene glycol …

Entry of nanoparticles into cells: The importance of nanoparticle properties

J Zhao, MH Stenzel - Polymer Chemistry, 2018 - pubs.rsc.org
Knowledge of the interactions between nanoparticles (NPs) and cell membranes is of great
importance for the design of safe and efficient nanomedicines. Extensive studies aimed at …

Gold nanomaterials at work in biomedicine

X Yang, M Yang, B Pang, M Vara, Y **a - Chemical reviews, 2015 - ACS Publications
Gold is a precious metal with a characteristic bright and beautiful hue known as the golden
yellow color.(1) As of 2012, a total of 174,100 tons of Au has been mined in human history …

Nanoparticle colloidal stability in cell culture media and impact on cellular interactions

TL Moore, L Rodriguez-Lorenzo, V Hirsch… - Chemical Society …, 2015 - pubs.rsc.org
Nanomaterials are finding increasing use for biomedical applications such as imaging,
diagnostics, and drug delivery. While it is well understood that nanoparticle (NP) physico …