Adenosine receptor antagonists: Recent advances and therapeutic perspective
Adenosine is an endogenous purine-based nucleoside expressed nearly in all body tissues.
It regulates various body functions by activating four G-protein coupled receptors, A 1, A 2A …
It regulates various body functions by activating four G-protein coupled receptors, A 1, A 2A …
Recent developments in new therapeutic agents against Alzheimer and Parkinson diseases: in-silico approaches
P Cruz-Vicente, LA Passarinha, S Silvestre, E Gallardo - Molecules, 2021 - mdpi.com
Neurodegenerative diseases (ND), including Alzheimer's (AD) and Parkinson's Disease
(PD), are becoming increasingly more common and are recognized as a social problem in …
(PD), are becoming increasingly more common and are recognized as a social problem in …
Methylxanthines and neurodegenerative diseases: an update
Methylxanthines (MTX) are purine derived xanthine derivatives. Whereas naturally occurring
methylxanthines like caffeine, theophylline or theobromine are widely consumed in food …
methylxanthines like caffeine, theophylline or theobromine are widely consumed in food …
Recent advances in the biological significance of xanthine and its derivatives: a review
Xanthine is the most ubiquitous heterocyclic aromatic compound and have attracted much
synthetic interest due to their numerous pharmacological activities. It is one of the principal …
synthetic interest due to their numerous pharmacological activities. It is one of the principal …
Drug Development for Alzheimer's and Parkinson's Disease: Where Do We Go Now?
L Sequeira, S Benfeito, C Fernandes, I Lima, J Peixoto… - Pharmaceutics, 2024 - mdpi.com
Neurodegenerative diseases (NDs) are a set of progressive, chronic, and incurable
diseases characterized by the gradual loss of neurons, culminating in the decline of …
diseases characterized by the gradual loss of neurons, culminating in the decline of …
Synthesis, QSAR modeling, and molecular docking of novel fused 7‐deazaxanthine derivatives as adenosine A2A receptor antagonists
Predictive QSAR models for the search of new adenosine A2A receptor antagonists were
developed by using OCHEM platform. The predictive ability of the regression models has …
developed by using OCHEM platform. The predictive ability of the regression models has …
Once Upon a Time Adenosine and Its Receptors: Historical Survey and Perspectives as Potential Targets for Therapy in Human Diseases
D Catarzi, F Varano, S Calenda, E Vigiani… - Purinergic Receptors and …, 2023 - Springer
Endogenous autacoid adenosine plays important physiological roles in various tissues and
organs by acting through A1, A2A, A2B, and A3 receptors. Dysregulated extracellular …
organs by acting through A1, A2A, A2B, and A3 receptors. Dysregulated extracellular …
Koffein, Schokolade und Adenosin A2A Rezeptorantagonisten in der Behandlung des Parkinson Syndroms
H Reichmann - Fortschritte der Neurologie· Psychiatrie, 2023 - thieme-connect.com
Hintergrund Patienten mit einem idiopathischen Parkinson-Syndrom können offenbar vom
Koffeinkonsum profitieren, wie bereits eine Reihe experimenteller und klinischer Studien …
Koffeinkonsum profitieren, wie bereits eine Reihe experimenteller und klinischer Studien …
[ЦИТИРОВАНИЕ][C] Drug Development for Alzheimer's and Parkinson's Disease: Where Do We Go Now? Pharmaceutics 2024, 16, 708
Neurodegenerative diseases (NDs) are a set of progressive, chronic, and incurable
diseases characterized by the gradual loss of neurons, culminating in the decline of …
diseases characterized by the gradual loss of neurons, culminating in the decline of …