Recent progress toward microfluidic quality control testing of radiopharmaceuticals

NS Ha, S Sadeghi, RM Van Dam - Micromachines, 2017 - mdpi.com
Radiopharmaceuticals labeled with short-lived positron-emitting or gamma-emitting isotopes
are injected into patients just prior to performing positron emission tomography (PET) or …

Microfluidic radiobioassays: a radiometric detection tool for understanding cellular physiology and pharmacokinetics

Z Liu, X Lan - Lab on a Chip, 2019 - pubs.rsc.org
The investigation of molecular uptake and its kinetics in cells is valuable for understanding
the cellular physiological status, the observation of drug interventions, and the development …

Cerenkov radiation imaging as a method for quantitative measurements of beta particles in a microfluidic chip

JS Cho, R Taschereau, S Olma, K Liu… - Physics in Medicine …, 2009 - iopscience.iop.org
It has been observed that microfluidic chips used for synthesizing 18 F-labeled compounds
demonstrate visible light emission without nearby scintillators or fluorescent materials. The …

A mini-panel PET scanner-based microfluidic radiobioassay system allowing high-throughput imaging of real-time cellular pharmacokinetics

Z Liu, P Zhang, H Ji, Y Long, B **g, L Wan, D **, R An… - Lab on a Chip, 2020 - pubs.rsc.org
On-chip radiometric detection of biological samples using radiotracers has become an
emerging research field known as microfluidic radiobioassays. Performing parallel …

High efficiency microfluidic beta detector for pharmacokinetic studies in small animals

L Convert, F Girard-Baril, A Renaudin, É Grondin… - Nuclear Instruments and …, 2011 - Elsevier
New radiotracers are continuously being developed to improve diagnostic efficiency using
Single Photon Emission Computed Tomography (SPECT) or Positron Emission Tomography …

Microfluidic beta and conversion electron radiation detector for preclinical pharmacokinetic studies with PET and SPECT radiotracers

L Convert, F Girard-Baril, V Boisselle… - … & Medical Imaging …, 2010 - ieeexplore.ieee.org
The characterization of new radiotracer pharmacokinetics in small animals is very
challenging because of the small volume of blood available. For this purpose, a microfluidic …

[KNJIGA][B] Microfluidics for the analysis and synthesis of radiopharmaceuticals

N Ha - 2018 - search.proquest.com
Radiopharmaceuticals labeled with short-lived positron-emitting or gamma-emitting isotopes
are injected into patients just prior to performing a positron emission tomography (PET) or …

Radioactivity detection in a target fluid in a fluid communication passageway with a region of scintillator material and a solid-state light-sensor element

SJ Archibald, D Jenkins, N Yavuzkanat… - US Patent …, 2020 - Google Patents
The present invention relates to a method and apparatus for detecting radioactivity. In
particular, but not exclusively, the present invention relates to the detection of radioactivity in …

Silicon photomultipliers for determining position of microfluidic radioactive samples

B Salvador, D Escalante, L Fernández… - … on Electron Devices …, 2018 - ieeexplore.ieee.org
An on-chip sensing circuit for measuring radioactivity in different positions of a microfluidic
device through the use of silicon photomultipliers (SiPM) is presented. It is intended for use …

[PDF][PDF] Escuela de Ingeniería y Ciencias

AC Garza - 2015 - researchgate.net
Los estudios sobre la distribución potencial de especies con respecto al cambio climático
han demostrado que las especies no son estáticas ante este fenómeno. Tomando en …