To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …

Increasing evidence suggests that abnormal cerebral glucose metabolism is largely present
in Alzheimer's disease (AD). The brain utilizes glucose as its main energy source and a …

Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every
cell type. EVs have diverse biological activities, ranging from roles in development and …

Besides motor symptoms, many individuals with Parkinson's disease develop cognitive
impairment perhaps due to coexisting α-synuclein and Alzheimer's disease pathologies and …

Extracellular vesicles (EVs) have emerged as mediators of cellular communication, in part
via the delivery of associated microRNAs (miRNAs), small non-coding RNAs that regulate …

Isolation of neuron‐derived extracellular vesicles (NDEVs) with L1 Cell Adhesion Molecule
(L1CAM)‐specific antibodies has been widely used to identify blood biomarkers of CNS …

Chimeric antigen receptors (CARs) are widely used by T cells (CAR-T cells), natural killer
cells dendritic cells and macrophages, and they are of great importance in cellular …

Background: The ADRB3 (β3-adrenergic receptors), which is predominantly expressed in
brown adipose tissue (BAT), can activate BAT and improve metabolic health. Previous …

Purpose: FGFR1 overexpression has been associated with endocrine resistance in ER+
breast cancer. We found FGFR1 localized in the nucleus of breast cancer cells in primary …

Extracellular vesicles (EVs) are membrane-enclosed nanoparticles that contain various
biomolecules, including nucleic acids, proteins and lipids, and are manufactured and …