The plant pentacyclic alkaloid camptothecin and its structural analogs were extensively
studied. These compounds are interesting due to the antitumor activity associated with their …

The present study is designed to explore the potential application of graphitic carbon nitride
(g-C3N4) for an anti-cancer Lonidamine drug-delivery by using DFT B3LYP/6-31G** level of …

To reduce the environmental pollution caused by organic solvents and improve the
extraction efficiency, a range of imidazolium-based ionic liquid (IL) combinations of [Omim]+ …

UV–Vis spectra of camptothecin (CPT) in toluene, acetone, ethanol, acetonitrile,
dimethylsulfoxide and aqueous solutions are investigated by UV–Vis spectroscopy and DFT …

The evaluation of drug levels is important for personalized therapeutic approaches
particularly in cancer care. To this end electrochemistry provides simplicity, low cost, high …

Two camptothecin derivatives, 10-cyclohexyl-7-methyl-20 (S)-camptothecin and 7-methyl-10-
morpholino-20 (S)-camptothecin, were synthesized and their differences in solubility were …

Using DOSY NMR and MALDI‐TOF MS techniques, we present evidence that quaternary
trimethylammonium salts of topotecan,[TPT‐NMe3]+ X−(X= CF3SO3, HCOO), bind …

A reaction mechanism of the anticancer agent camptothecin (CPT)'s E-ring-opening has
been studied by DFT method and IEF-PCM solvation model. Our results indicate that under …

Presently, there is a great demand for small probe molecules that can be used for two-
photon excitation microscopy (TPM)-based monitoring of intracellular and intraorganelle …

Abstracts Free radical substitution reaction, which has low energy barrier and takes place in
mild reaction conditions, is an important method for camptothecin's modification. The …