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The Enterococcus: a model of adaptability to its environment
The genus Enterococcus comprises a ubiquitous group of Gram-positive bacteria that are of
great relevance to human health for their role as major causative agents of health care …
great relevance to human health for their role as major causative agents of health care …
The impact of insertion sequences on bacterial genome plasticity and adaptability
Transposable elements (TE), small mobile genetic elements unable to exist independently
of the host genome, were initially believed to be exclusively deleterious genomic parasites …
of the host genome, were initially believed to be exclusively deleterious genomic parasites …
Phage-plasmids promote recombination and emergence of phages and plasmids
Phages and plasmids are regarded as distinct types of mobile genetic elements that drive
bacterial evolution by horizontal gene transfer. However, the distinction between both types …
bacterial evolution by horizontal gene transfer. However, the distinction between both types …
[HTML][HTML] Short prokaryotic Argonaute systems trigger cell death upon detection of invading DNA
Argonaute proteins use single-stranded RNA or DNA guides to target complementary
nucleic acids. This allows eukaryotic Argonaute proteins to mediate RNA interference and …
nucleic acids. This allows eukaryotic Argonaute proteins to mediate RNA interference and …
PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures
Plasmids are mobile genetics elements that play an important role in the environmental
adaptation of microorganisms. Although plasmids are usually analyzed in cultured …
adaptation of microorganisms. Although plasmids are usually analyzed in cultured …
Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data
We present a hierarchical genome-assembly process (HGAP) for high-quality de novo
microbial genome assemblies using only a single, long-insert shotgun DNA library in …
microbial genome assemblies using only a single, long-insert shotgun DNA library in …
Evolutionary pathways and trajectories in antibiotic resistance
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …
provided a wealth of information, but knowledge regarding “what happened” has precluded …
Acquired antibiotic resistance genes: an overview
In this review an overview is given on antibiotic resistance (AR) mechanisms with special
attentions to the AR genes described so far preceded by a short introduction on the …
attentions to the AR genes described so far preceded by a short introduction on the …
Bacterial genome instability
E Darmon, DRF Leach - Microbiology and Molecular Biology …, 2014 - journals.asm.org
Bacterial genomes are remarkably stable from one generation to the next but are plastic on
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …
Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition
ABSTRACT Carbapenemase-producing Enterobacteriaceae (CPE), which are resistant to
most or all known antibiotics, constitute a global threat to public health. Transposable …
most or all known antibiotics, constitute a global threat to public health. Transposable …