An overview of cancer health disparities: new approaches and insights and why they matter

TZ Minas, M Kiely, A Ajao, S Ambs - Carcinogenesis, 2021 - academic.oup.com
Cancer health disparities remain stubbornly entrenched in the US health care system. The
Affordable Care Act was legislation to target these disparities in health outcomes. Expanded …

Breast cancer in low-and middle-income countries: why we need pathology capability to solve this challenge

YM Martei, LE Pace, JE Brock… - Clinics in laboratory …, 2017 - pmc.ncbi.nlm.nih.gov
The global burden of cancer is increasing worldwide, with most new cancer cases and
cancer-related mortality occurring in low-and middle-income countries (LMIC). 1 It is …

Immune response and inflammation in cancer health disparities

M Kiely, B Lord, S Ambs - Trends in cancer, 2022 - cell.com
Cancer death rates vary among population groups. Underserved populations continue to
experience an excessive burden of lethal cancers that is largely explained by health-care …

[HTML][HTML] Tumor-associated macrophages induce endocrine therapy resistance in ER+ breast cancer cells

AM Castellaro, MC Rodriguez-Baili, CE Di Tada, GA Gil - Cancers, 2019 - mdpi.com
Antiestrogenic adjuvant treatments are first-line therapies in patients with breast cancer
positive for estrogen receptor (ER+). Improvement of their treatment strategies is needed …

Tumor-associated CD163+ macrophage as a predictor of tumor spread through air spaces and with CD25+ lymphocyte as a prognostic factor in resected stage I lung …

C Yoshida, K Kadota, K Yamada, S Fujimoto, E Ibuki… - Lung Cancer, 2022 - Elsevier
Objective Lung cancer can spread in numerous ways, including spread through air spaces
(STAS). A high number of CD68+ tumor-associated macrophages (TAMs), which creates a …

Population-specific mutation patterns in breast tumors from African American, European American, and Kenyan patients

W Tang, F Zhang, JS Byun, TH Dorsey… - Cancer Research …, 2023 - aacrjournals.org
Women of African descent have the highest breast cancer mortality in the United States and
are more likely than women from other population groups to develop an aggressive disease …

Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa

M Bauer, M Vetter, K Stückrath… - Cancer immunology …, 2023 - aacrjournals.org
The low overall survival rates of patients with breast cancer in sub-Saharan Africa (SSA) are
driven by regionally differing tumor biology, advanced tumor stages at diagnosis, and limited …

Characterization of hormonal receptors and human epidermal growth factor receptor-2 in tissues of women with breast cancer at Muhimbili National Hospital, Dar es …

AR Mwakigonja, NE Lushina, A Mwanga - Infectious agents and cancer, 2017 - Springer
Background Breast cancer is a leading cause of morbidity and deaths among women
worldwide. In Tanzania there is no published data on human epidermal growth receptor-2 …

[HTML][HTML] Analysis of tumor biology to advance cancer health disparity research

CJ Smith, TZ Minas, S Ambs - The American Journal of Pathology, 2018 - Elsevier
Cancer mortality rates in the United States continue to decline. Reductions in tobacco use,
uptake of preventive measures, adoption of early detection methods, and better treatments …

Metastatic breast cancer in Kenya: presentation, pathologic characteristics, and patterns—findings from a tertiary cancer center

E Ekpe, AJ Shaikh, J Shah, JS Jacobson… - Journal of global …, 2019 - ascopubs.org
PURPOSE The purpose of this research was to describe the sociodemographic and clinical
characteristics of Kenyan women with metastatic breast cancer diagnosed and treated at …