Salmonella SPI-2 type III secretion system effectors: molecular mechanisms and physiological consequences

E Jennings, TLM Thurston, DW Holden - Cell host & microbe, 2017 - cell.com
Serovars of Salmonella enterica cause both gastrointestinal and systemic diseases in a
broad range of mammalian hosts, including humans. Salmonella virulence depends in part …

Typhoidal Salmonella: Distinctive virulence factors and pathogenesis

R Johnson, E Mylona, G Frankel - Cellular microbiology, 2018 - Wiley Online Library
Although nontyphoidal Salmonella (NTS; including Salmonella Typhimurium) mainly cause
gastroenteritis, typhoidal serovars (Salmonella Typhi and Salmonella Paratyphi A) cause …

Speaking the host language: how Salmonella effector proteins manipulate the host

TD Pillay, SU Hettiarachchi, J Gan… - …, 2023 - microbiologyresearch.org
Salmonella injects over 40 virulence factors, termed effectors, into host cells to subvert
diverse host cellular processes. Of these 40 Salmonella effectors, at least 25 have been …

Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation

M Bawn, NF Alikhan, G Thilliez, M Kirkwood… - PLoS …, 2020 - journals.plos.org
Salmonella enterica serotype Typhimurium (S. Typhimurium) is a leading cause of
gastroenteritis and bacteraemia worldwide, and a model organism for the study of host …

Host Cell Death Responses to Non-typhoidal Salmonella Infection

MA Wemyss, JS Pearson - Frontiers in immunology, 2019 - frontiersin.org
Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) is a Gram-
negative bacterium with a broad host range that causes non-typhoidal salmonellosis in …

SseK1 and SseK3 type III secretion system effectors inhibit NF-κB signaling and necroptotic cell death in Salmonella-infected macrophages

RA Günster, SA Matthews, DW Holden… - Infection and …, 2017 - journals.asm.org
Within host cells such as macrophages, Salmonella enterica translocates virulence (effector)
proteins across its vacuolar membrane via the SPI-2 type III secretion system. Previously, it …

Prophages in Salmonella enterica: a driving force in resha** the genome and physiology of their bacterial host?

A Wahl, A Battesti, M Ansaldi - Molecular microbiology, 2019 - Wiley Online Library
Thanks to the exponentially increasing number of publicly available bacterial genome
sequences, one can now estimate the important contribution of integrated viral sequences to …

Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages

TA Stepien, LA Singletary, FE Guerra, JE Karlinsey… - Mbio, 2024 - journals.asm.org
ABSTRACT Salmonella serovars Typhi and Paratyphi cause a prolonged illness known as
enteric fever, whereas other serovars cause acute gastroenteritis. Mechanisms responsible …

Autophagy and Ubiquitination in Salmonella Infection and the Related Inflammatory Responses

L Wang, J Yan, H Niu, R Huang, S Wu - Frontiers in cellular and …, 2018 - frontiersin.org
Salmonellae are facultative intracellular pathogens that cause globally distributed diseases
with massive morbidity and mortality in humans and animals. In the past decades, numerous …

Molecular mechanisms used by Salmonella to evade the immune system

J Bernal-Bayard, F Ramos-Morales - Current issues in molecular biology, 2018 - mdpi.com
Human and animal pathogens are able to circumvent, at least temporarily, the sophisticated
immune defences of their hosts. Several serovars of the Gram-negative bacterium …