Understanding of molecular mechanisms of tumor growth has an increasing impact on the
development of diagnostics and targeted therapy of human neoplasia. In this review, we …

The primary hurdle in the treatment of cancer is acquisition of resistance by the tumor cells
toward multiple drugs and selectively targeting the cancer stem cells. This problem was …

Recently, the interplay between autophagy and apoptosis has become an important factor in
chemotherapy for cancer treatment. Inhibition of autophagy may be an effective strategy to …

This combinational therapy is mainly aimed for complete eradication of tumor by killing both
cancer cells and cancer stem cells. Salinomycin (SLM) was targeted towards cancer stem …

Ovarian cancer is one of the most important malignancies, and the origin, detection, and
pathogenesis of epithelial ovarian cancer remain elusive. Although many cancer drugs have …

Salinomycin, traditionally used as an anti-coccidial drug, has recently been shown to
possess anti-cancer and anti-cancer stem cell (CSC) effects, as well as activities to …

Breast cancer (BC) is the most frequent cancer among women worldwide and is the leading
cause of cancer-related deaths in women. Cancer cells with stem cell-like features and …

The polyphenolic component of citrus fruits, hesperetin (Hst), is a metabolite of hesperidin. In
this study, we examined the effect of varying doses and exposure times of hesperetin on …

Background In this study we investigated the in vitro and in vivo anticancer effect of carnosol,
a naturally occurring polyphenol, in triple negative breast cancer. Results We found that …

The connections between cancer stem cells (CSCs) and epithelial-mesenchymal transition
(EMT) is critical in cancer initiation, progression, metastasis, and therapy resistance, making …