Importance Approximately 18.6 million people worldwide are affected by a diabetic foot ulcer
each year, including 1.6 million people in the United States. These ulcers precede 80% of …

Diabetic foot ulcers (DFU) are a major source of preventable morbidity in adults with
diabetes. Consequences of foot ulcers include decline in functional status, infection …

Diabetic foot ulcers often become infected, leading to treatment complications and increased
risk of loss of limb. Therapeutics to manage infection and simultaneously promote healing …

Bacterial infection and the ever-increasing bacterial resistance have imposed severe threat
to human health. And bacterial contamination could significantly menace the wound healing …

High glucose-induced vascular endothelial injury is a major pathological factor involved in
non-healing diabetic wounds. To interrupt this pathological process, we design an all …

Wound healing is highly specialized dynamic multiple phase process for the repair of
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …

Significance: Chronic wounds impact the quality of life (QoL) of nearly 2.5% of the total
population in the United States and the management of wounds has a significant economic …

Diabetes mellitus is a costly disease and nearly one-third of these costs are attributed to
management of diabetic foot disease including chronic, non-healing, diabetic foot ulcers …

Foot ulcers are one of the most common and severe complication of diabetes mellitus with
significant resultant morbidity and mortality. Multiple factors impair wound healing include …

Aim To estimate the long‐term mortality and risk factors in patients with diabetic foot ulcer
(DFU). Methods We systematically searched Medline (PubMed), Embase, Scopus, Web of …