Antipsychotic drugs are the mainstay in the treatment of schizophrenia. However, one-third
of patients do not show adequate improvement in positive symptoms with non-clozapine …

Functional neuroimaging emerged with great promise and has provided fundamental
insights into the neurobiology of schizophrenia. However, it has faced challenges and …

Structural hippocampal abnormalities are common in many neurological and psychiatric
disorders, and variation in hippocampal measures is related to cognitive performance and …

Background: Hippocampal disturbances are important in the pathophysiology of both
schizophrenia and major depressive disorder (MDD). Imaging studies have shown selective …

Electroconvulsive therapy (ECT) is effective against treatment-resistant psychosis, but its
mechanisms remain unclear. Conventional volumetry studies have revealed plasticity in …

Objective Electroconvulsive therapy (ECT) has been the most potent treatment option for
treatment-resistant schizophrenia (TRS). However, the underlying neural mechanisms of …

Background: Antipsychotic treatment has been shown to yield hippocampal and amygdalar
volumetric changes in first-episode schizophrenia (FES). However, whether antipsychotic …

Background Abnormalities in brain regions involved in the pathophysiology of schizophrenia
(SCZ) may present insight into individual clinical symptoms. Specifically, functional …

Objective Previous studies have established significant differences in the neuroimaging
characteristics between healthy controls (HCs) and patients with schizophrenia (SCZ) …

Past evidence suggests that hippocampal subregions, namely the anterior and posterior
parts, may be engaged in distinct networks underlying the memory functions which may be …