Pancreatic cancer in chronic pancreatitis: pathogenesis and diagnostic approach

G Le Cosquer, C Maulat, B Bournet, P Cordelier… - Cancers, 2023 - mdpi.com
Simple Summary Chronic alcoholic pancreatitis displays a cumulative risk of pancreatic
cancer estimated at 4% after 15 to 20 years, this risk being higher for hereditary pancreatitis …

Metabolomic machine learning predictor for diagnosis and prognosis of gastric cancer

Y Chen, B Wang, Y Zhao, X Shao, M Wang… - Nature …, 2024 - nature.com
Gastric cancer (GC) represents a significant burden of cancer-related mortality worldwide,
underscoring an urgent need for the development of early detection strategies and precise …

Screening for pancreatic cancer has the potential to save lives, but is it practical?

BL Mazer, JW Lee, NJ Roberts, LC Chu… - Expert review of …, 2023 - Taylor & Francis
Introduction Most patients with pancreatic cancer present with advanced stage, incurable
disease. However, patients with high-grade precancerous lesions and many patients with …

Improving the prognosis of pancreatic cancer: insights from epidemiology, genomic alterations, and therapeutic challenges

Z Jiang, X Zheng, M Li, M Liu - Frontiers of Medicine, 2023 - Springer
Pancreatic cancer, notorious for its late diagnosis and aggressive progression, poses a
substantial challenge owing to scarce treatment alternatives. This review endeavors to …

[HTML][HTML] Evaluating metabolite-based biomarkers for early diagnosis of pancreatic cancer: a systematic review

G Perazzoli, OM García-Valdeavero, M Pena, J Prados… - Metabolites, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with five-year
survival rates around 10%. The only curative option remains complete surgical resection, but …

Metabolomic biomarkers in liquid biopsy: accurate cancer diagnosis and prognosis monitoring

W Wang, S Zhen, Y **, L Wang, Y Zhang - Frontiers in Oncology, 2024 - frontiersin.org
Liquid biopsy, a novel detection method, has recently become an active research area in
clinical cancer owing to its unique advantages. Studies on circulating free DNA, circulating …

[HTML][HTML] Understanding the conundrum of pancreatic cancer in the omics sciences era

A Nicoletti, M Paratore, F Vitale, M Negri… - International Journal of …, 2024 - mdpi.com
Pancreatic cancer (PC) is an increasing cause of cancer-related death, with a dismal
prognosis caused by its aggressive biology, the lack of clinical symptoms in the early phases …

Managing complications of chronic pancreatitis: a guide for the gastroenterologist

G Capurso, M Tacelli, G Vanella… - Expert review of …, 2023 - Taylor & Francis
Introduction Chronic pancreatitis is a heterogeneous and complex syndrome that, in most
cases, causes pain as a cardinal symptom and affects both the morphology and function of …

[HTML][HTML] Serum cytokine profiles in patients with pancreatic cancer and chronic pancreatitis

M Lanki, H Mustonen, M Salmi, S Jalkanen, C Haglund… - Pancreatology, 2023 - Elsevier
Background Chronic pancreatitis (CP) may cause tumor-like lesions, creating a challenge in
distinguishing between CP and pancreatic ductal adenocarcinoma (PDAC) in a patient …

[HTML][HTML] Multi-omics profiling to identify early plasma biomarkers in pre-diagnostic pancreatic ductal adenocarcinoma: a nested case-control study

E Borgmästars, B Ulfenborg, M Johansson… - Translational …, 2024 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with poor survival.
Novel biomarkers are urgently needed to improve the outcome through early detection …