Multifactorial basis and therapeutic strategies in metabolism-related diseases

JVS Guerra, MMG Dias, AJVC Brilhante, MF Terra… - Nutrients, 2021 - mdpi.com
Throughout the 20th and 21st centuries, the incidence of non-communicable diseases
(NCDs), also known as chronic diseases, has been increasing worldwide. Changes in …

The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders

C Del Río, E Millan, V Garcia, G Appendino… - Biochemical …, 2018 - Elsevier
The skin is the largest organ of the body and has a complex and very active structure that
contributes to homeostasis and provides the first line defense against injury and infection. In …

The endocannabinoid anandamide mediates anti‐inflammatory effects through activation of NR4A nuclear receptors

T Teichmann, B Pflüger‐Müller… - British Journal of …, 2024 - Wiley Online Library
Background and purpose Endocannabinoids are lipid mediators, which elicit complex
biological effects that extend beyond the central nervous system. Tissue concentrations of …

[HTML][HTML] Profiling plasma N-Acylethanolamine levels and their ratios as a biomarker of obesity and dysmetabolism

F Fanelli, M Mezzullo, A Repaci, I Belluomo… - Molecular …, 2018 - Elsevier
Objective N-acylethanolamines play different roles in energy balance; anandamide (AEA)
stimulates energy intake and storage, N-palmitoylethanolamide (PEA) counters …

The endocannabinoid system in cardiovascular function: novel insights and clinical implications

S Sierra, N Luquin, J Navarro-Otano - Clinical Autonomic Research, 2018 - Springer
Rationale Cardiovascular disease is now recognized as the number one cause of death in
the world, and the size of the population at risk continues to increase rapidly. The …

Considerations for cannabinoids in perioperative care by anesthesiologists

K Laudanski, J Wain - Journal of Clinical Medicine, 2022 - mdpi.com
Increased usage of recreational and medically indicated cannabinoid compounds has been
an undeniable reality for anesthesiologists in recent years. These compounds' complicated …

Anandamide and endocannabinoid system: An attractive therapeutic approach for cardiovascular disease

VM Martín Giménez, SE Noriega… - Therapeutic …, 2018 - journals.sagepub.com
Cardiovascular disease is currently not adequately managed and has become one of the
main causes of morbidity and mortality worldwide. Current therapies are inadequate in terms …

Cannabinoids in the cardiovascular system

WSV Ho, MEM Kelly - Advances in Pharmacology, 2017 - Elsevier
Cannabinoids are known to modulate cardiovascular functions including heart rate, vascular
tone, and blood pressure in humans and animal models. Essential components of the …

Cannabinoids and cardiovascular system

AI Bondarenko - Recent Advances in Cannabinoid Physiology and …, 2019 - Springer
Cannabinoids influence cardiovascular variables in health and disease via multiple
mechanisms. The chapter covers the impact of cannabinoids on cardiovascular function in …

The endocannabinoid system:'NO'longer anonymous in the control of nitrergic signalling?

C Lipina, HS Hundal - Journal of Molecular Cell Biology, 2017 - academic.oup.com
The endocannabinoid system (ECS) is a key cellular signalling system that has been
implicated in the regulation of diverse cellular functions. Importantly, growing evidence …