There is extensive experimental evidence that oxidative damage permanently occurs to
lipids of cellular membranes, proteins, and DNA. In nuclear and mitochondrial DNA, 8 …

Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

Abstract Fine particle (PM 2.5) samples were collected simultaneously at three urban sites
(Shanghai, Nan**g, and Hangzhou) and one rural site near Ningbo in the Yangtze River …

Tobacco smoke contains many toxic, carcinogenic and mutagenic chemicals, as well as
stable and unstable free radicals and reactive oxygen species (ROS) in the particulate and …

Particulates are small particles of solid or liquid suspended in liquid or air. In vitro studies
show that particles generate reactive oxygen species, deplete endogenous antioxidants …

Particulate air pollution (PM) is an important environmental health risk factor for many
different diseases. This is indicated by numerous epidemiological studies on associations …

Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

Fuchs endothelial corneal dystrophy (FECD) is a progressive, blinding disease
characterized by corneal endothelial (CE) cell apoptosis. Corneal transplantation is the only …

Air pollution, which includes particulate matter (PM), is classified in group 1 as a carcinogen
to humans by the International Agency for Research in Cancer. Specifically, PM exposure …

Occupational exposure to airborne nickel is associated with an elevated risk for respiratory
tract diseases including lung cancer. Therefore, the increased production of Ni-containing …