Neutrophils promptly accumulate in large numbers at sites of tissue injury. Injuries to the skin
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …

Background The intestinal tract is a complicated ecosystem with dynamic homeostasis via
interaction of intestine and microbiota. Inflammatory bowel disease (IBD) is chronic intestinal …

Milk-derived extracellular vesicles (mEVs) have been proposed as a potential nanomedicine
for intestinal disorders; however, their impact on intestinal barrier integrity in gut …

Pathogenic gut microbiota is responsible for a few debilitating gastrointestinal diseases.
While the host immune cells do produce extracellular vesicles to counteract some …

Neutrophil (PMN) infiltration of the intestinal mucosa is a hallmark of tissue injury associated
with inflammatory bowel diseases (IBDs). The pathological effects of PMNs are largely …

It is well established that natural killer (NK) cells are involved in both innate and adaptive
immunity. Indeed, they can recognize molecules induced at the cell surface by stress signals …

Simple Summary For millennia, humankind has had a symbiotic relationship with different
bacterial species, called the microbiota. Our microbiota can affect the homeostasis, the …

Osteoarthritis (OA) has become recognized as a low-grade inflammatory state. Inflammatory
infiltration of the synovium by macrophages, T cells, B cells, and other immune cells is often …

Inflammation plays a decisive role in inducing tumorigenesis, promoting tumor development,
tumor invasion and migration. The interaction of cancer cells with their surrounding stromal …

Major depressive disorder (MDD) is a serious mental disease characterized by depressed
mood, loss of interest and suicidal ideation. Its rising prevalence has rendered MDD one of …