Models of psychedelic drug action: modulation of cortical-subcortical circuits

MK Doss, MB Madden, A Gaddis, MB Nebel… - Brain, 2022 - academic.oup.com
Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …

Untangling the cortico-thalamo-cortical loop: cellular pieces of a knotty circuit puzzle

GMG Shepherd, N Yamawaki - Nature Reviews Neuroscience, 2021 - nature.com
Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Morphological diversity of single neurons in molecularly defined cell types

H Peng, P **e, L Liu, X Kuang, Y Wang, L Qu, H Gong… - Nature, 2021 - nature.com
Dendritic and axonal morphology reflects the input and output of neurons and is a defining
feature of neuronal types,, yet our knowledge of its diversity remains limited. Here, to …

Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings

NA Steinmetz, C Aydin, A Lebedeva, M Okun… - Science, 2021 - science.org
INTRODUCTION Electrode arrays based on complementary metal-oxide semiconductor
silicon fabrication technology, such as Neuropixels probes, have enabled recordings of …

The influence of cortical activity on perception depends on behavioral state and sensory context

LE Russell, M Fişek, Z Yang, LP Tan… - Nature …, 2024 - nature.com
The mechanistic link between neural circuit activity and behavior remains unclear. While
manipulating cortical activity can bias certain behaviors and elicit artificial percepts, some …

[HTML][HTML] Cooperative thalamocortical circuit mechanism for sensory prediction errors

S Furutachi, AD Franklin, AM Aldea, TD Mrsic-Flogel… - Nature, 2024 - nature.com
The brain functions as a prediction machine, utilizing an internal model of the world to
anticipate sensations and the outcomes of our actions. Discrepancies between expected …

Circuitry underlying experience-dependent plasticity in the mouse visual system

BM Hooks, C Chen - Neuron, 2020 - cell.com
Since the discovery of ocular dominance plasticity, neuroscientists have understood that
changes in visual experience during a discrete developmental time, the critical period …

Neurons and networks in the entorhinal cortex: A reappraisal of the lateral and medial entorhinal subdivisions mediating parallel cortical pathways

ES Nilssen, TP Doan, MJ Nigro, S Ohara… - …, 2019 - Wiley Online Library
In this review, we aim to reappraise the organization of intrinsic and extrinsic networks of the
entorhinal cortex with a focus on the concept of parallel cortical connectivity streams. The …

Distinguishing externally from saccade-induced motion in visual cortex

SK Miura, M Scanziani - Nature, 2022 - nature.com
Distinguishing sensory stimuli caused by changes in the environment from those caused by
an animal's own actions is a hallmark of sensory processing. Saccades are rapid eye …

Early-stage visual perception impairment in schizophrenia, bottom-up and back again

P Adámek, V Langová, J Horáček - Schizophrenia, 2022 - nature.com
Visual perception is one of the basic tools for exploring the world. However, in
schizophrenia, this modality is disrupted. So far, there has been no clear answer as to …