Cerebral small vessel disease, hypertension, and vascular contributions to cognitive impairment and dementia
Hypertension-associated cerebral small vessel disease is a common finding in older people.
Strongly associated with age and hypertension, small vessel disease is found at autopsy in …
Strongly associated with age and hypertension, small vessel disease is found at autopsy in …
Antithrombotic Therapy for Primary and Secondary Prevention of Ischemic Stroke: JACC State-of-the-Art Review
Stroke is a devastating condition with significant morbidity and mortality worldwide.
Antithrombotic therapy plays a crucial role in both primary and secondary prevention of …
Antithrombotic therapy plays a crucial role in both primary and secondary prevention of …
Tetrazole derivatives in the management of neurological disorders: Recent advances on synthesis and pharmacological aspects
Neurological disorders are the leading cause of a large number of mortalities and
morbidities. Nitrogen heterocyclic compounds have been pivotal in exhibiting wide array of …
morbidities. Nitrogen heterocyclic compounds have been pivotal in exhibiting wide array of …
Cerebrovascular effects of sildenafil in small vessel disease: the OxHARP trial
BACKGROUND: Vascular cognitive impairment due to cerebral small vessel disease is
associated with cerebral pulsatility, white matter hypoperfusion, and reduced …
associated with cerebral pulsatility, white matter hypoperfusion, and reduced …
The role of cilostazol, a phosphodiesterase-3 inhibitor, in the development of atherosclerosis and vascular biology: a review with meta-analysis
Atherosclerotic cardiovascular disease (ASCVD) stands as the leading global cause of
mortality. Addressing this vital and pervasive condition requires a multifaceted approach, in …
mortality. Addressing this vital and pervasive condition requires a multifaceted approach, in …
Associations between neurovascular coupling and cerebral small vessel disease: a systematic review and meta-analysis
Purpose: The pathogenesis of cerebral small vessel disease (cSVD) remains elusive
despite evidence of an association between white matter hyperintensities (WMH) and …
despite evidence of an association between white matter hyperintensities (WMH) and …
Current and future treatments of vascular cognitive impairment
Vascular cognitive impairment (VCI) traditionally encompasses a variety of cerebrovascular
pathologies that contribute to varying levels of cognitive impairment, ranging from subtle to …
pathologies that contribute to varying levels of cognitive impairment, ranging from subtle to …
[HTML][HTML] A sco** review on biomarkers of endothelial dysfunction in small vessel disease: molecular insights from human studies
Small vessel disease (SVD) is a highly prevalent disorder of the brain's microvessels and a
common cause of dementia as well as ischaemic and haemorrhagic strokes. Though much …
common cause of dementia as well as ischaemic and haemorrhagic strokes. Though much …
Advances in nitric oxide regulators for the treatment of ischemic stroke
J Wu, J Jia, D Ji, W Jiao, Z Huang, Y Zhang - European Journal of …, 2023 - Elsevier
Ischemic stroke (IS) is a life-threatening disease worldwide. Nitric oxide (NO) derived from l-
arginine catalyzed by NO synthase (NOS) is closely associated with IS. Three isomers of …
arginine catalyzed by NO synthase (NOS) is closely associated with IS. Three isomers of …
Endothelial cells as key players in cerebral small vessel disease
Cerebral small vessel disease (SVD) is a vascular disorder that increases the risk of stroke
and dementia and is diagnosed through brain MRI. Current primary prevention and …
and dementia and is diagnosed through brain MRI. Current primary prevention and …