High-resolution native mass spectrometry
Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …
[HTML][HTML] IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy
S Shkunnikova, A Mijakovac, L Sironic, M Hanic… - Biotechnology …, 2023 - Elsevier
Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …
for the structure and function of IgG. IgG glycome is relatively stable in the state of …
Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition
Here we have generated 3D structures of glycoforms of the spike (S) glycoprotein from
SARS-CoV-2, based on reported 3D structures and glycomics data for the protein produced …
SARS-CoV-2, based on reported 3D structures and glycomics data for the protein produced …
Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis
Glycoproteomics is a powerful yet analytically challenging research tool. Software packages
aiding the interpretation of complex glycopeptide tandem mass spectra have appeared, but …
aiding the interpretation of complex glycopeptide tandem mass spectra have appeared, but …
Virus-receptor interactions of glycosylated SARS-CoV-2 spike and human ACE2 receptor
The SARS-CoV-2 betacoronavirus uses its highly glycosylated trimeric Spike protein to bind
to the cell surface receptor angiotensin converting enzyme 2 (ACE2) glycoprotein and …
to the cell surface receptor angiotensin converting enzyme 2 (ACE2) glycoprotein and …
The history of IgG glycosylation and where we are now
BA Cobb - Glycobiology, 2020 - academic.oup.com
IgG glycosylation is currently at the forefront of both immunology and glycobiology, likely due
in part to the widespread and growing use of antibodies as drugs. For over four decades, it …
in part to the widespread and growing use of antibodies as drugs. For over four decades, it …
Altered N‐glycosylation profiles as potential biomarkers and drug targets in diabetes
N‐glycosylation is a ubiquitous protein modification, and N‐glycosylation profiles are
emerging as both biomarkers and functional effectors in various types of diabetes. Genome …
emerging as both biomarkers and functional effectors in various types of diabetes. Genome …
Plasma N-Glycans as Emerging Biomarkers of Cardiometabolic Risk: A Prospective Investigation in the EPIC-Potsdam Cohort Study
C Wittenbecher, T Štambuk, O Kuxhaus… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Plasma protein N-glycan profiling integrates information on enzymatic protein
glycosylation, which is a highly controlled ubiquitous posttranslational modification. Here we …
glycosylation, which is a highly controlled ubiquitous posttranslational modification. Here we …
Glycosylation in SARS-CoV-2 variants: A path to infection and recovery
Glycan is an essential molecule that controls and drives life in a precise direction. The
paucity of research in glycobiology may impede the significance of its role in the pandemic …
paucity of research in glycobiology may impede the significance of its role in the pandemic …
Immunoglobulin G glycans–Biomarkers and molecular effectors of aging
Immunoglobulin G (IgG) antibodies are post-translationally modified by the addition of
complex carbohydrate molecules–glycans, which have profound effects on the IgG function …
complex carbohydrate molecules–glycans, which have profound effects on the IgG function …