Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022 - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Smart biomaterials for articular cartilage repair and regeneration

Z Gu, J Wang, Y Fu, H Pan, H He… - Advanced Functional …, 2023 - Wiley Online Library
Articular cartilage defects bring about disability and worldwide socioeconomic loss,
therefore, articular cartilage repair and regeneration is recognized as a global issue …

The advances in nanomedicine for bone and cartilage repair

K Qiao, L Xu, J Tang, Q Wang, KS Lim… - Journal of …, 2022 - Springer
With the gradual demographic shift toward an aging and obese society, an increasing
number of patients are suffering from bone and cartilage injuries. However, conventional …

[HTML][HTML] Intra-articular nanoparticles based therapies for osteoarthritis and rheumatoid arthritis management

J Wen, H Li, H Dai, S Hua, X Long, H Li, S Ivanovski… - Materials Today Bio, 2023 - Elsevier
Osteoarthritis (OA) and rheumatoid arthritis (RA) are chronic and progressive inflammatory
joint diseases that affect a large population worldwide. Intra-articular administration of …

Chondrocyte membrane–coated nanoparticles promote drug retention and halt cartilage damage in rat and canine osteoarthritis

R Deng, R Zhao, Z Zhang, Y Chen, M Yang… - Science Translational …, 2024 - science.org
Osteoarthritis (OA) is a chronic joint disease characterized by progressive degeneration of
articular cartilage. A challenge in the development of disease-modifying drugs is effective …

Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage

K Zhou, C Yang, K Shi, Y Liu, D Hu, X He, Y Yang… - Biomaterials, 2023 - Elsevier
Osteoarthritis (OA) is a common joint condition that is a leading cause of disability
worldwide. There are currently no disease-modifying treatments for osteoarthritis, which is …

[HTML][HTML] Advanced Hydrogel systems for mandibular reconstruction

J Guo, H Yao, X Li, L Chang, Z Wang, W Zhu, Y Su… - Bioactive materials, 2023 - Elsevier
Mandibular defect becomes a prevalent maxillofacial disease resulting in mandibular
dysfunctions and huge psychological burdens to the patients. Considering the routine …

Microenvironment-responsive nanocarriers for targeted bone disease therapy

M Li, B Yu, S Wang, F Zhou, J Cui, J Su - Nano Today, 2023 - Elsevier
Nanomedicines with controlled drug release have received increasing attention as an
advanced therapeutic strategy for bone diseases. To traverse biological barriers towards …

Instructive cartilage regeneration modalities with advanced therapeutic implantations under abnormal conditions

Z Wang, H Le, Y Wang, H Liu, Z Li, X Yang, C Wang… - Bioactive Materials, 2022 - Elsevier
The development of interdisciplinary biomedical engineering brings significant
breakthroughs to the field of cartilage regeneration. However, cartilage defects are …