Nitrogen-containing heterocyclic rings are common structural components of marketed
drugs. Among these heterocycles, imidazole/fused imidazole rings are present in a wide …

Heterocyclic derivatives as a major group of organic compounds are enormously used for a
wide range of pharmaceutical and industrial applications. They are known for their biological …

In this study,(E)-2-phenyl-N-(thiophen-2-ylmethylene) imidazo [1, 2-a] pyrimidin-3-amine (3)
is synthesized, and detailed spectral characterizations using 1H NMR, 13C NMR, mass, and …

Background: Heterocycles play a major role in many fields of biochemical and physiological
such as amino acids, DNA bases, vitamins, endogenous neurotransmitters, etc …

Cancer is the world's biggest global health concern. The prevalence and mortality rates of
cancer remain high despite significant progress in cancer therapy. The search for more …

Pyrimidine-fused derivatives that are the inextricable part of DNA and RNA play a key role in
the normal life cycle of cells. Pyrimidine-fused dinitrogenous penta-heterocycles, including …

An efficient method for the synthesis of a new class of α-aminophosphonates of imatinib
derivative has been developed in one-pot Kabachnik-Fields reaction of N-(5-amino-2-methyl …

Cancer has emerged as one of the leading causes of death globally, partly due to the steady
rise in anticancer drug resistance. Pyrimidine and pyrimidine-fused heterocycles are some …

Designed, synthesized a series of novel imidazo [1, 2‐a] pyridine derivatives and evaluated
for their in vitro cytotoxicity. Fluorine containing compounds,(2‐fluorophenyl)(4‐(2‐(pyridin‐2 …

A convenient and effective synthesis of imidazo [1, 2-a] pyrimidine derivatives has been
developed under microwave irradiations using Al2O3 as a catalyst in solvent-free …