Increased risk of cardiovascular complications in chronic kidney disease: introduction to a compendium
H Noels, J Jankowski - Circulation Research, 2023 - Am Heart Assoc
Chronic kidney disease (CKD) is defined by kid-ney damage or a reduced kidney filtration
function with an estimated glomerular filtration rate< 60 mL/(min· 1.73 m²) for> 3 months …
function with an estimated glomerular filtration rate< 60 mL/(min· 1.73 m²) for> 3 months …
Mechanisms of heart failure and chronic kidney disease protection by SGLT2 inhibitors in nondiabetic conditions
ACC Girardi, JZ Polidoro, PC Castro… - … of Physiology-Cell …, 2024 - journals.physiology.org
Sodium-glucose cotransporter 2 inhibitors (SGLT2is), initially developed for type 2 diabetes
(T2D) treatment, have demonstrated significant cardiovascular and renal benefits in heart …
(T2D) treatment, have demonstrated significant cardiovascular and renal benefits in heart …
Roles of AhR/CYP1s signaling pathway mediated ROS production in uremic cardiomyopathy
W Lu, S Cheng, J Xu, Z **ao, Y Yu, Q **e, Y Fang… - Toxicology Letters, 2024 - Elsevier
Purpose Uremic cardiomyopathy (UCM) is the leading cause of chronic kidney disease
(CKD) related mortality. Uremic toxins including indoxyl sulfate (IS) play important role …
(CKD) related mortality. Uremic toxins including indoxyl sulfate (IS) play important role …
[HTML][HTML] Biochanin A inhibits cardiac hypertrophy and fibrosis in vivo and in vitro
Z Feng, N Zhang, J Bai, Q Lin, Y **e, Y **a - Biomedicine & …, 2024 - Elsevier
The heart undergoes pathological cardiac hypertrophy as an adaptive response to
prolonged pathological stimulation, leading to cardiomyocyte hypertrophy, fibroblast …
prolonged pathological stimulation, leading to cardiomyocyte hypertrophy, fibroblast …
Unraveling Chronic Cardiovascular and Kidney Disorder through the Butterfly Effect
D Bedo, T Beaudrey, N Florens - Diagnostics, 2024 - mdpi.com
Chronic Cardiovascular and Kidney Disorder (CCKD) represents a growing challenge in
healthcare, characterized by the complex interplay between heart and kidney diseases. This …
healthcare, characterized by the complex interplay between heart and kidney diseases. This …
Incident heart failure in chronic kidney disease: proteomics informs biology and risk stratification
Abstract Background and Aims Incident heart failure (HF) among individuals with chronic
kidney disease (CKD) incurs hospitalizations that burden patients and health care systems …
kidney disease (CKD) incurs hospitalizations that burden patients and health care systems …
The Worsening of Myocardial Ischemia–Reperfusion Injury in Uremic Cardiomyopathy is Further Aggravated by PM2.5 Exposure: Mitochondria Serve as the Central …
Uremic cardiomyopathy (UC) represents a complex syndrome characterized by different
cardiac complications, including systolic and diastolic dysfunction, left ventricular …
cardiac complications, including systolic and diastolic dysfunction, left ventricular …
[HTML][HTML] Fibroblast Growth Factor (FGF) 23 and FGF Receptor 4 promote cardiac metabolic remodeling in chronic kidney disease
MA Fuchs, EJ Burke, N Latic, S Murray, H Li… - Research …, 2023 - ncbi.nlm.nih.gov
Chronic kidney disease (CKD) is a global health epidemic that significantly increases
mortality due to cardiovascular disease. Left ventricular hypertrophy (LVH) is an important …
mortality due to cardiovascular disease. Left ventricular hypertrophy (LVH) is an important …
Altered systemic bioenergetic reserve in chronic kidney disease predisposes hearts to worse functional outcomes
M Young, M Aastrup, N Patel, F Cullen, ESS Hansen… - bioRxiv, 2024 - biorxiv.org
Chronic kidney disease (CKD) is the tenth biggest killer worldwide and is projected to be the
fifth leading cause of mortality by 2040. CKD is an inherently systemic disease with …
fifth leading cause of mortality by 2040. CKD is an inherently systemic disease with …
The protective effect of sKlotho on uremic cardiomyopathy
XU Shengchun, Z **aoliang - Chinese Journal of Nephrology, Dialysis & …, 2024 - njcndt.com
sKlotho, a soluble form of the anti-aging protein α-Klotho, exerts multifaceted biological
effects. Chronic kidney disease (CKD), marked by a deficiency in sKlotho, leads to the …
effects. Chronic kidney disease (CKD), marked by a deficiency in sKlotho, leads to the …