Biological systems are composed of heterogeneous populations of cells that
intercommunicate to form a functional living tissue. Biological function varies greatly across …

The early 2000s brought a new age in the field of mass spectrometry (MS) with the
introduction of ambient ionization MS techniques. As defined by one of its early visionaries …

Mass spectrometry imaging (MSI) enables label-free spatial map** of hundreds of
biomolecules in tissue sections. This capability provides valuable information on tissue …

Previously, we have demonstrated native mass spectrometry imaging (native MSI) in which
the spatial distribution of proteins maintained in their native-like, folded conformations was …

K. pneumoniae sequence type 258 (Kp ST258) is a major cause of healthcare-associated
pneumonia. However, it remains unclear how it causes protracted courses of infection in …

Unraveling the complexity of the lipidome requires the development of novel approaches for
the structural characterization of lipid species with isomer‐level discrimination. Herein, we …

Mass spectrometry imaging (MSI) combines molecular and spatial information in a valuable
tool for a wide range of applications. Matrix‐assisted laser desorption/ionization (MALDI) is …

Simultaneous spatial localization and structural characterization of molecules in complex
biological samples currently represents an analytical challenge for mass spectrometry …

Mass spectrometry imaging (MSI) has become a widespread analytical technique to perform
nonlabeled spatial molecular identification. The Achilles' heel of MSI is the annotation and …

Label-free spatial map** of the noncovalent interactions of proteins in their tissue
environment has the potential to revolutionize life sciences research by providing …