[HTML][HTML] Herbal concoction unveiled: a computational analysis of phytochemicals' pharmacokinetic and toxicological profiles using novel approach methodologies …

M Rai, AV Singh, N Paudel, A Kanase, E Falletta… - Current Research in …, 2023 - Elsevier
Herbal medications have an extensive history of use in treating various diseases, attributed
to their perceived efficacy and safety. Traditional medicine practitioners and contemporary …

Antidiabetic Activity, Molecular Docking, and ADMET Properties of Compounds Isolated from Bioactive Ethyl Acetate Fraction of Ficus lutea Leaf Extract

OO Olaokun, MS Zubair - Molecules, 2023 - mdpi.com
Diabetes contributes to the rising global death rate. Despite scientific advancements in
understanding and managing diabetes, no single therapeutic agent has been identified to …

Antiviral activities of olive oil apigenin and taxifolin against SARS-CoV-2 RNA-dependent RNA polymerase (RdRP): In silico, pharmacokinetic, ADMET, and in-vitro …

S Selim, M Albqmi, A Alanazi, Y Alruwaili… - Cogent Food & …, 2023 - Taylor & Francis
A novel coronavirus strain called SARS-CoV-2 first appeared in China in December 2019.
Natural products are significant sources of prospective and new antiviral medications, and …

Valorization of the essential oil from Drypetes gossweileri S. Moore (Putranjivaceae): in vitro, in vivo, and in silico nematicidal activity

JP Mbula, MF Andres, EM Kitete, NG Kasiama… - Frontiers in Plant …, 2023 - frontiersin.org
The chemical composition, insect antifeedant, in vtro/in vivo nematicidal activity,
phytotoxicity, and in silico nematicidal activity of the essential oil (EO) of the African …

Molecular docking and dynamic studies of novel phytoconstituents in an investigation of the potential inhibition of protein kinase C-beta II in diabetic neuropathy

VK Maurya, S Kumar, M Singh… - Journal of Molecular …, 2023 - pubs.thesciencein.org
Diabetic neuropathy, a debilitating complication of diabetes, necessitates innovative
therapeutic interventions targeting Protein Kinase C-beta II (PKC-beta II). This study derives …

Anticancer, antioxidant, and antimicrobial properties of solvent extract of Lobophora variegata through in vitro and in silico studies with major phytoconstituents

N Palaniappan, B Balasubramanian, M Arunkumar… - Food Bioscience, 2022 - Elsevier
Seaweeds possess a wide range of bioactive compounds which have been play a vital role
in production of novel pharmaceutical and nutraceutical products resources. The present …

In silico drug repurposing of anticancer drug 5-FU and analogues against SARS-CoV-2 main protease: Molecular docking, molecular dynamics simulation …

A Matondo, W Dendera, BK Isamura… - … and Applications in …, 2022 - Taylor & Francis
Background Since the last COVID-19 outbreak, several approaches have been given a try to
quickly tackle this global calamity. One of the well-established strategies is the drug …

Cedrus deodara (Roxb. ex D. Don) G. Don bark fraction ameliorates metabolic, endocrine and ovarian dynamics in rats experiencing polycystic ovarian syndrome

A Bisht, R Gururani, S Jain, R Shukla, J Dwivedi… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance In the Ayurvedic system of medicine, Cedrus
deodara bark has been utilized as a folk medicine to remove ovarian cysts and treat infertility …

[HTML][HTML] Phytochemical study and evaluation of the antidiabetic and antihyperglycemic activities of the fruit extracts of Physalis peruviana L.(Solanaceae)

DST Tshibangu, FS Kavugho, CN Kabengele… - Phytomedicine Plus, 2025 - Elsevier
The aim of the study was to evaluate the antidiabetic and antihyperglycemic activities of
Physalis peruviana L.(PP) fruit extracts as well as to determine the structure-activity …

Molecular docking and molecular dynamics simulation studies of the interaction of anti-oral cancer plant Curcuma longa derived-compounds with human epidermal …

MM Charly, JPKTN Ngbolua, JPS Issouradi… - Journal of Proteins and …, 2024 - Springer
Background Oral cancer encompasses a heterogeneous group of malignant tumors
affecting various regions of the oral cavity. This study aims to demonstrate the efficacy of …