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Bridging the genomic data gap in Africa: implications for global disease burdens
This paper highlights the gap in the use of genomic data of Africans for global research
efforts for disease cures. Genomic data represents an important tool used in disease …
efforts for disease cures. Genomic data represents an important tool used in disease …
Understanding biases and disparities in radiology AI datasets: a review
Artificial intelligence (AI) continues to show great potential in disease detection and
diagnosis on medical imaging with increasingly high accuracy. An important component of …
diagnosis on medical imaging with increasingly high accuracy. An important component of …
[HTML][HTML] Uganda genome resource enables insights into population history and genomic discovery in Africa
Genomic studies in African populations provide unique opportunities to understand disease
etiology, human diversity, and population history. In the largest study of its kind, comprising …
etiology, human diversity, and population history. In the largest study of its kind, comprising …
Host and microbiome genome-wide association studies: current state and challenges
D Awany, I Allali, S Dalvie, S Hemmings… - Frontiers in …, 2019 - frontiersin.org
The involvement of the microbiome in health and disease is well established. Microbiome
genome-wide association studies (mGWAS) are used to elucidate the interaction of host …
genome-wide association studies (mGWAS) are used to elucidate the interaction of host …
Alcohol dependence genetics: lessons learned from genome‐wide association studies (GWAS) and post‐GWAS analyses
AB Hart, HR Kranzler - Alcoholism: clinical and experimental …, 2015 - Wiley Online Library
Background Alcohol dependence (AD) is a complex psychiatric disorder and a significant
public health problem. Twin and family‐based studies have consistently estimated its …
public health problem. Twin and family‐based studies have consistently estimated its …
Gut microbiome features associated with liver fibrosis in Hispanics, a population at high risk for fatty liver disease
Abstract Background and Aims Hispanics are disproportionately affected by NAFLD, liver
fibrosis, cirrhosis, and HCC. Preventive strategies and noninvasive means to identify those …
fibrosis, cirrhosis, and HCC. Preventive strategies and noninvasive means to identify those …
Gut microbiome alterations associated with diabetes in Mexican Americans in South Texas
Mexican Americans have a high prevalence of diabetes and burden of diabetes-related
complications, highlighting the need for novel preventive strategies and noninvasive …
complications, highlighting the need for novel preventive strategies and noninvasive …
Potential use of clinical polygenic risk scores in psychiatry–ethical implications and communicating high polygenic risk
Psychiatric disorders present distinct clinical challenges which are partly attributable to their
multifactorial aetiology and the absence of laboratory tests that can be used to confirm …
multifactorial aetiology and the absence of laboratory tests that can be used to confirm …
Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture
The heritability of susceptibility to tuberculosis (TB) disease has been well recognized. Over
100 genes have been studied as candidates for TB susceptibility, and several variants were …
100 genes have been studied as candidates for TB susceptibility, and several variants were …
Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?
Single nucleotide polymorphisms (SNPs) have been classically used for dissecting various
human complex disorders using candidate gene studies. During the last decade, large scale …
human complex disorders using candidate gene studies. During the last decade, large scale …