Mixed selectivity: Cellular computations for complexity

KM Tye, EK Miller, FH Taschbach, MK Benna, M Rigotti… - Neuron, 2024 - cell.com
The property of mixed selectivity has been discussed at a computational level and offers a
strategy to maximize computational power by adding versatility to the functional role of each …

Computational role of structure in neural activity and connectivity

S Ostojic, S Fusi - Trends in Cognitive Sciences, 2024 - cell.com
One major challenge of neuroscience is identifying structure in seemingly disorganized
neural activity. Different types of structure have different computational implications that can …

Tuned geometries of hippocampal representations meet the computational demands of social memory

LM Boyle, L Posani, S Irfan, SA Siegelbaum, S Fusi - Neuron, 2024 - cell.com
Social memory consists of two processes: the detection of familiar compared with novel
conspecifics and the detailed recollection of past social episodes. We investigated the …

Abstract representations emerge in human hippocampal neurons during inference

HS Courellis, J Minxha, AR Cardenas, DL Kimmel… - Nature, 2024 - nature.com
Humans have the remarkable cognitive capacity to rapidly adapt to changing environments.
Central to this capacity is the ability to form high-level, abstract representations that take …

Neural representational geometries reflect behavioral differences in monkeys and recurrent neural networks

V Fascianelli, A Battista, F Stefanini, S Tsujimoto… - Nature …, 2024 - nature.com
Animals likely use a variety of strategies to solve laboratory tasks. Traditionally, combined
analysis of behavioral and neural recording data across subjects employing different …

Modeling similarity and psychological space

BD Roads, BC Love - Annual Review of Psychology, 2024 - annualreviews.org
Similarity and categorization are fundamental processes in human cognition that help
complex organisms make sense of the cacophony of information in their environment. These …

Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum suppresses interaction with familiar mice

NS de León Reyes, PS Díaz, R Nogueira, A Ruiz-Pino… - Cell, 2023 - cell.com
Social preference, the decision to interact with one member of the same species over
another, is critical to optimize social interactions. Thus, adult rodents favor interacting with …

The implications of categorical and category-free mixed selectivity on representational geometries

MT Kaufman, MK Benna, M Rigotti, F Stefanini… - Current opinion in …, 2022 - Elsevier
The firing rates of individual neurons displaying mixed selectivity are modulated by multiple
task variables. When mixed selectivity is nonlinear, it confers an advantage by generating a …

Abstract representations emerge naturally in neural networks trained to perform multiple tasks

WJ Johnston, S Fusi - Nature Communications, 2023 - nature.com
Humans and other animals demonstrate a remarkable ability to generalize knowledge
across distinct contexts and objects during natural behavior. We posit that this ability to …

[HTML][HTML] Disinhibition by VIP interneurons is orthogonal to cross-modal attentional modulation in primary visual cortex

D Myers-Joseph, KA Wilmes, M Fernandez-Otero… - Neuron, 2024 - cell.com
Attentional modulation of sensory processing is a key feature of cognition; however, its
neural circuit basis is poorly understood. A candidate mechanism is the disinhibition of …