Harnessing genomic information for livestock improvement

M Georges, C Charlier, B Hayes - Nature Reviews Genetics, 2019 - nature.com
The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …

1000 bull genomes project to map simple and complex genetic traits in cattle: applications and outcomes

BJ Hayes, HD Daetwyler - Annual review of animal biosciences, 2019 - annualreviews.org
The 1000 Bull Genomes Project is a collection of whole-genome sequences from 2,703
individuals capturing a significant proportion of the world's cattle diversity. So far, 84 million …

Molecular genetic variation of animals and plants under domestication

L Andersson, M Purugganan - Proceedings of the National …, 2022 - National Acad Sciences
Domesticated plants and animals played crucial roles as models for evolutionary change by
means of natural selection and for establishing the rules of inheritance, originally proposed …

A comprehensive biomedical variant catalogue based on whole genome sequences of 582 dogs and eight wolves

V Jagannathan, C Drögemüller, T Leeb… - Animal …, 2019 - Wiley Online Library
The domestic dog serves as an excellent model to investigate the genetic basis of disease.
More than 400 heritable traits analogous to human diseases have been described in dogs …

Zebrafish models for skeletal and Extraskeletal Osteogenesis Imperfecta features: unveiling pathophysiology and paving the way for Drug Discovery

C Masiero, C Aresi, A Forlino, F Tonelli - Calcified Tissue International, 2024 - Springer
In the last decades, the easy genetic manipulation, the external fertilization, the high
percentage of homology with human genes and the reduced husbandry costs compared to …

Founder-specific inbreeding depression affects racing performance in Thoroughbred horses

ET Todd, SYW Ho, PC Thomson, RA Ang, BD Velie… - Scientific reports, 2018 - nature.com
The Thoroughbred horse has played an important role in both sporting and economic
aspects of society since the establishment of the breed in the 1700s. The extensive pedigree …

The intronic branch point sequence is under strong evolutionary constraint in the bovine and human genome

NK Kadri, XM Mapel, H Pausch - Communications biology, 2021 - nature.com
The branch point sequence is a cis-acting intronic motif required for mRNA splicing. Despite
their functional importance, branch point sequences are not routinely annotated. Here we …

Large-scale detection and characterization of interchromosomal rearrangements in normozoospermic bulls using massive genotype and phenotype data sets

J Jourdain, H Barasc, T Faraut, A Calgaro… - Genome …, 2023 - genome.cshlp.org
In this paper, we developed a highly sensitive approach to detect interchromosomal
rearrangements in cattle by searching for abnormal linkage disequilibrium patterns between …

Massive detection of cryptic recessive genetic defects in dairy cattle mining millions of life histories

F Besnard, A Guintard, C Grohs, L Guzylack-Piriou… - Genome Biology, 2024 - Springer
Background Dairy cattle breeds are populations of limited effective size, subject to recurrent
outbreaks of recessive defects that are commonly studied using positional cloning. However …

Identification of candidate genes on the basis of SNP by time-lagged heat stress interactions for milk production traits in German Holstein cattle

K Halli, SF Vanvanhossou, M Bohlouli, S König, T Yin - PLoS One, 2021 - journals.plos.org
The aim of this study was to estimate genotype by time-lagged heat stress (HS) variance
components as well as main and interaction SNP-marker effects for maternal HS during the …